不同水化方式预防对比剂肾病的对比研究  

The comparative study on the prevention of contrast induced nephropathy with different hydration methods

作　　者：彭嘉丽[1] 李军娇[1] 商晓蕾[2] 王竟[3] 

机构地区：[1]宁夏医科大学总医院心脑血管病医院放射科,宁夏银川750002 [2]宁夏医科大学总医院心脑血管病医院呼吸与危重症医学科,宁夏银川750002 [3]宁夏医科大学,宁夏银川750004

出　　处：《宁夏医学杂志》2017年第5期417-419,共3页Ningxia Medical Journal

摘　　要：目的分析不同水化方式对预防对比剂肾病(CIN)的效果差异,探讨水化方式的选择应用原则及方法。方法根据采用的水化方式不同,将研究病例分为口服水化组90例和静脉水化组90例2组,分析2种不同水化方式患者对比剂使用前后血肌酐、尿素氮的变化,计算2组患者CIN的发病率,并对结果进行统计分析。结果口服水化途径有3例患者发生CIN,静脉水化途径有2例患者发生CIN,2组患者3个时段的血肌酐、尿素氮的变化在组间和组内差异均无统计学意义(P>0.05)。结论两种水化途径均可有效预防CIN高危人群使用对比剂后对肾功能的损害,可根据患者情况选择合适的水化途径。Objective To analyze the effects of different hydration methods on the prevention of contrast induced nephropathy, and to explore the principles and methods of the application of the hydration method. Methods The patients were divide the into oral hydration group （ n = 90） and intravenous hydration group （ n = 90） according to the different hydration methods, and the changes of the serum creatinine and urea nitrogen two in patients before and after using contrast agents with two different hydration, the incidence of CIN in two groups were analyzed. Results There were 3 cases with CIN by oral hydration, and there were 2 cases with CIN by intravenous hydration, there was no significant difference in the incidence of contrast induced nephropathy. Conclusion Both two methods can effectively prevent the damage of renal function in patients with high risk of CIN after the use of contrast agents.

关 键 词：对比剂肾病 预防 水化 

分 类 号：R692[医药卫生—泌尿科学]