纤维蛋白原、D-D等指标在2型糖尿病下肢血管病变筛查中应用价值  

Application Value of Fibrinogen and D-D Index in Screening of Type 2 Diabetic Lower Extremity Vascular Lesions

作　　者：魏兆丽[1] 高爱滨[1] 潘学飞[1] 

机构地区：[1]山东省滨州市中心医院内分泌科,山东滨州251700

出　　处：《世界最新医学信息文摘》2017年第4期11-11,13,共2页World Latest Medicine Information Electronic Version

摘　　要：目的探讨纤维蛋白原(Fib)及D二聚体(D-D)在糖尿病下肢血管病变中的应用价值。方法对住院的119例2型糖尿病患者进行纤维蛋白原及D二聚体等检查和双下肢血管彩色多普勒超声检查。结果合并下肢血管病变的2型糖尿病组患者的血浆Fib(3.38±1.21)g/L、D-D(0.98±0.89)mg/L,对照组Fib(3.05±1.13)g/L、D-D(0.84±0.76)mg/L,研究组均高于对照组(P<0.05)。结论糖尿病合并下肢血管病变患者D-D及FIB水平均显著升高,存在显著正相关。应积极在糖尿病病程长、合并高血压等患者中常规检查,以便于下肢血管病变筛查。Objective To investigate the clinical value offibrinogen （Fib） and D-dimer （D-D） in diabetic patients with lower extremity vascular diseases. Methods 119 patients with type 2 diabetes mellitus were examined by fibrinogen and D-dimer and color Doppler ultrasonography. Results The levels of plasma fibrinogen of the Patients with type 2 diabetes mellitus combined with lower extremity vascular disease were 3.38 ± 1.21g/L, D-D 0.98 ± 0.89mg/L,and plasma fibrinogen of control group were 3.05± 1.13g/L, D-D 0.84 ± 0.76 mg/L, respectively, The levels of Fib in the study group were higher than those in the control group （.P〈0.05） . Conclusion D-D and FIB levels in patients with diabetes mellitus complicated with lower extremity vascular disease were significantly increased, and there was significant positive correlation. It should be used actively in the long duration of diabetes, hypertension and other patients with routine examination in order to facilitate lower limb vascular disease screening.

关 键 词：2型糖尿病 糖尿病下肢血管病变 纤维蛋白原 D二聚体 

分 类 号：R587.1[医药卫生—内分泌]