高血压病患者并发中心性肥胖的相关因素及其腹围与动态血压相关性  

Association between abdominal girth and ambulatory blood pressure in patients with central obesity combined with hypertension

作　　者：万进[1] 王光耀[2] 何安霞[1] 

机构地区：[1]南京中医药大学附属江苏省中医院心内科,江苏南京210029 [2]南京中医药大学基础医学院中基内经教研室,江苏南京210023

出　　处：《心脏杂志》2017年第3期317-321,共5页Chinese Heart Journal

摘　　要：目的分析高血压病患者并发中心性肥胖的相关因素及其腹围和动态血压(ABPM)的相关性。方法回顾性分析100例中心性肥胖并发高血压病患者(病例组)的资料,分为男性组(n=50)、女性组(n=50)。另设无中心性肥胖的高血压病患者作为对照组(n=100)。比较腹围和ABPM的关系。腹围和血压的相关性研究采用直线相关分析,并采取控制影响因素的偏相关分析。结果男性组和女性组年龄匹配。二组24h收缩压(SBP)均值、白天SBP均值、夜晚SBP均值最高SBP均值均增高。二组比较差异无统计学意义。腹围与24SBP均值、白天SBP均值、夜晚SBP均值、最高SBP均值呈正相关(男性r=0.282、r=0.360、r=0.238、r=0.380,均P<0.05;女性r=0.350、r=0.342、r=0.335、r=0.344,均P<0.05)。腹围与昼夜节律呈负相关,男性r=-0.278/-0.058;女性r=-0.264/-0.027,均P<0.05/P>0.05。腹围与24h SBP负荷均值呈正相关(男性r=0.339、女性r=0.321,P<0.05)。结论中心性肥胖并发高血压病患者腹围与收缩压、收缩压负荷、昼夜节律相关。AIM To study the relation between abdominal girth and ambulatory blood pressure monitoring （ABPM） in patients with central obesity combined with hypertension. METHODS A retrospective study of 100 cases of central obesity combined with hypertension was conducted with 50 males and 50 females. The control group consisted of 100 hypertensive patents with no central obesity. The association between abdominal girth and ABPM was studied with a linear correlation and with partial correlation to control the influencing factors. RESULTS Males and females were age matched. Average 24-h systolic blood pres- sure （SBP） and average diurnal and nocturnal SBP all increased in both groups, but without statistical significance between groups （t = 0. 869, t = 1. 347, t = 0. 340, t = 0. 140, P 〉 0. 05）. Abdominal girth was positively associated with average 24-h SBP, average diurnal and nocturnal SBP and average SBP max （male： r=0.282, r=0.360, r=0.238, r=0.380, P〈0.05; female： r=0.350, r--0.342, r= 0. 335, r = 0. 344, P 〈 0. 05 ）. Abdominal girth was negatively associated with circadian rhythms （ male r = - 0. 278/- 0. 058 ; female r = - 0. 264/- 0. 027, all P 〈 0. 05/P 〉 O. 05 ） but was positively associ- ated with average 24-h SBP load （male r = 0. 339, female r = 0. 321, P 〈 0. 05）. CONCLUSION Ab-dominal girth of patients with central obesity combined with hypertension is associated with SBP, SBP load and circadian rhythms, indicating abdominal girth should be controlled.

关 键 词：动态血压 高血压 原发性 中心型肥胖 腹围 

分 类 号：R540.41[医药卫生—心血管疾病]