诺舒阻抗控制子宫内膜消融术治疗异常子宫出血的临床疗效评价  

Evaluation of clinical therapeutic effect of NovaSure impedance-controlled endometrial ablation in treatment of abnormal uterine bleeding

作　　者：林启平[1] 郑敏慧[1] 林霞[1] 孙广范[1] 苏彩虹[1] 

机构地区：[1]中山市博爱医院妇产科,广东中山528400

出　　处：《中国妇幼保健》2017年第10期2225-2227,共3页Maternal and Child Health Care of China

基　　金：中山市医学科研项目(2015A020017)

摘　　要：目的探讨评价诺舒阻抗控制子宫内膜消融术治疗异常子宫出血的临床效果。方法将中山市博爱医院生殖内分泌科收治的66例异常子宫出血患者分为诺舒组(41例)和常规组(25例),前者采用诺舒阻抗控制子宫内膜消融术治疗,后者采用常规热球子宫内膜切除术治疗,分析对比两组临床疗效。结果诺舒组手术时间(OT)、术中出血量(BL)、术后住院时间(HST)和月经恢复时间(MRT)均明显少于常规组,差异均有统计学意义(t=10.890、9.085、8.835、6.143,P<0.05);诺舒组痊愈、有效和无效与常规组数据间等级比较差异有统计学意义(H=4.926,P<0.05),前者总有效率为95.12%,远高于后者的72.00%差异有统计学意义(χ~2=6.012,P<0.05);诺舒组下腹疼痛、子宫穿孔、宫腔积脓、宫腔感染等并发症发生率和常规组比较差异均无统计学意义(χ~2=0.346、1.123、1.123、0.874,P>0.05),前者并发症发生率为4.88%,与后者的12.00%比较差异无统计学意义(χ~2=1.406,P>0.05)。结论采用诺舒阻抗控制子宫内膜消融术对异常子宫出血患者进行治疗可显著改善整体疗效,还可减少创伤、促进术后恢复,该疗法安全可靠具有良好的应用价值。Objective To explore and evaluate the clinical therapeutic effect of NovaSure impedance-controlled endometrial ablation in treatment of abnormal uterine bleeding. Methods Sixty-six patients with abnormal uterine bleeding treated in Department of Reproductive Endocrinology in the hospital were selected and divided into NovaSure group （41 patients） and routine group （25 patients） . The patients in NovaSure group were treated with NovaSure impedance-controlled endometrial ablation, while the patients in routine group were treated with conventional thermal balloon endometrial resection. The clinical therapeutic effects were compared between the two groups. Results The operation time （OT）, blood loss （BL） , hospital-staying time （HST） , and menstruation recovery time （MRT） in NovaSure group were statistically significantly less than those in routine group （ t = 10. 890, 9.085,8. 835,6. 143, P〈0.05） . There were statistically significant differences in the degrees of recovery, effectiveness, and ineffectiveness between the two groups （ H= 4. 926, P〈0. 05 ） . The total effective rate in NovaSure group was 95. 12% , which was statistically significantly higher than that in routine group （ 72. 00% ） （χ^2= 6. 012, P〈 0. 05 ） . There was no statistically significant difference in the incidence rates of complications （ lower abdominal pain, uterine perforation, pyometra, and intrauterine infection） between the two groups （χ^2 =0. 346, 1. 123, 1. 123, 0. 874, P〉0. 05） . The total incidence rates of complications in NovaSure group and routine group were 4. 88% and 12.00% , respectively, there was no statistically significant difference between the two groups （χ^2 = 1. 406, P〉0. 05 ） . Conclusion NovaSure impedance-controlled endometrial ablation can significantly improve the total therapeutic effect, reduce trauma, and promote postoperative recovery in treatment of abnormal uterine bleeding, which is safe and reliable, the application value is good.

关 键 词：诺舒阻抗控制子宫内膜消融术 异常子宫出血 效果 

分 类 号：R713[医药卫生—妇产科学]