增强型体外反搏治疗急性缺血性卒中的临床疗效及预后评估  

The clinical effects and prognosis evaluation of enhanced external counterpulsation on acute cerebral ischemic stroke

作　　者：周国强[1] 黄宗青[1] 肖剑伟[1] 张娟[1] 刘淑娟[1] 王玉光[1] 晏晓琨 

机构地区：[1]中山大学附属第八医院神经内科,深圳518033

出　　处：《中国神经精神疾病杂志》2017年第3期147-151,共5页Chinese Journal of Nervous and Mental Diseases

基　　金：2015年深圳市知识创新计划基础研究项目(编号:JCYJ20150402145015987);2014年深圳市福田区公益性科研项目(编号:FTWS2014016)

摘　　要：目的探讨增强型体外反搏(enhanced external counterpulsation,EECP)对急性缺血性卒中患者临床治疗效果及预后的影响,为缺血性卒中患者的康复治疗提供进一步的临床证据。方法选取急性期缺血性卒中住院患者共171例,随机分为EECP治疗组87例,对照组84例,治疗组予常规治疗加上36 h的EECP治疗,对照组予常规治疗,分别比较两组在入院第1天、EECP治疗后、第3个月的美国国立卫生研究院卒中量表(NIHSS)及改良Rankin量表(mRS)的差别。结果与对照组比较,治疗组在36次EECP治疗后及第3个月的NIHSS评分下降更明显,有统计学差异,(治疗后:44.1%vs.31.5%;第3个月:55.6%vs.40.5%),P值均小于0.05;与对照组比较,发病第3个月,治疗组mRS的评分下降更明显(45.5%vs.30.5%),预后良好者的比率明显升高,差异有统计学意义,P值均小于0.05。结论 EECP治疗可以有效改善急性缺血性卒中患者神经功能缺损症状,促进康复,改善预后。Objective To explore the therapeutic effect and prognosis of enhanced external counterpulsation （EECP）on acute cerebral ischemic stroke, to provide clinical evidence for the treatment of patients with acute cerebral isehemic stroke. Methods Totall71 patients with acute cerebral ischemic stroke were enrolled and measured the NIHSS and mRS, before EECP, after36 hours EECP, and 3-month after attack. Then contrast the difference of these indicators. Result Compare with the control group, after EECP treatment and after 3-month attack, the scores of NIHSS were statistically significant, （ after EECP：44.1% vs 31.5% ;after 3-month attack：55.6% vs 40.5%）, （P〈 0.05 ）.Compare with the control group, after 3-month attack, the score of mRS in EECP group was declined statisti- cally significant,and the rate of favourable prognosis rise obviously （P〈0.05）. Conclusion EECP can effectively im- prove neurological function and promote health and improve prognosis in the patients with acute cerebral ischemic stroke.

关 键 词：增强型体外反搏 美国国立卫生研究院卒中量表 改良Rankin量表 临床疗效 缺血性卒中 预后 

分 类 号：R743.3[医药卫生—神经病学与精神病学]