抗菌药物应用对剖宫产术后患者的临床影响  被引量:8

Clinical effect of antimicrobial agents on patients after cesarean section

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作  者:吴星光[1] 

机构地区:[1]广东医学院附属深圳南山医院产科,广东深圳518051

出  处:《中国计划生育和妇产科》2017年第5期52-54,共3页Chinese Journal of Family Planning & Gynecotokology

摘  要:目的分析预防性应用抗菌药物对剖宫产术后患者抗感染的效果,探讨如何有效降低剖宫产术后感染率。方法选取2014年1月至2016年5月广东医学院附属深圳南山医院收治的剖宫产产妇62例,分成研究组(给予预防性抗菌药物)和对照组(未给予预防性抗菌药物),每组31例。对产妇的白细胞计数、排气时间、感染率、C反应蛋白(C-reactive protein,CRP)、清蛋白、前清蛋白等指标进行观察和比较。结果(1)研究组产妇的白细胞计数和排气时间均明显低于对照组(P<0.05),研究组无感染发生,明显低于对照组(12.90%)(P<0.05);(2)术前两组患者的CRP、清蛋白、前清蛋白等炎症因子水平比较,差异无统计学意义(P﹥0.05);术后研究组患者的CRP水平低于对照组,清蛋白和前清蛋白水平高于对照组(P<0.05)。结论给予预防性应用抗菌药物可以有效地降低产妇剖宫产术后感染率,控制产妇的炎症因子水平,是临床实践的理想选择之一。Objective To explore the effect of prophylactic antimicrobial agents on anti - infection after cesarean section in order to reduce the infection rate after cesarean section. Methods 62 cases of cesarean section parturients at A^liated Shenzhen Nanshan Hospital of Guangdong Medical College from January 2014 to May 2016 were selected and divided into study group ( given prophylactic antibiotics) and control group (not given prophylactic antibiotics). The maternal white blood cell count, exhaust time, infection rate and C -reactive protein( CRP), albumin, prealbumin etc. were observed and compared. Results (1) The maternal white blood cell count and exhaust time of the study group were significantly lower than those of the control group. There were no infection in 31 cases of the study group. There were 4 cases of infection in the 31 cases of the control group. The infection rate of the control group was 12. 90%. The infection rate of the study group was significantly lower than that of the control group and the difference was statistically significant(P 〈 0. 05 ); (2) Before surgery, there were no significant difference between the two groups with the CRP, albumin, prealbumin and inflammatory factor levels (P 〉 0. 05 ). After surgery, the CRP of the study group were lower than control group, the albumin, prealbumin and inflammatory factor levels were highter than control group, and the difference was statistically significant(P 〈 O. 05). Conclusion Giving the prophylactic application of antibiotics can effectively reduce maternal cesarean section infection rate, effectively control maternal levels of inflammatory factors and it is one of ideal ways for clinical practice.

关 键 词:预防性 抗菌药 剖宫产 炎症因子 感染 

分 类 号:R719.8[医药卫生—妇产科学]

 

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