组织多普勒成像联合MVF、PVF在吸毒者左心室舒张功能中的应用及评价  

Application and evaluation of tissue doppler imaging combined with MVF and PVF in left ventricular diastolic function of drug users

作　　者：孙燕[1] 游向东[2] 戚瑞祥[2] 

机构地区：[1]杭州市职业病防治院B超室,浙江杭州310014 [2]浙江大学医学院附属第二医院,浙江杭州310009

出　　处：《中国现代医生》2017年第12期129-132,136,F0003,共6页China Modern Doctor

基　　金：浙江省自然科学基金资助项目(LY14H180003)

摘　　要：目的探讨组织多普勒成像联合评价吸毒者左心室舒张功能的临床价值。方法选取89例吸毒患者分为三组及健康对照59例为研究对象。组织多普勒成像及MVF,PVF,测量二尖瓣E峰、A峰速度及速度之比(E/A);二尖瓣E峰减速时间DT;肺静脉收缩波、舒张波速度(S、D);肺静脉收缩波,舒张波流速之比(S/D);肺静脉心房收缩波速度(AR)、持续时间(Adur)。结果 (1)吸毒年龄小,吸毒时间长,左室舒张功能越差,左室壁增厚,左房、室增大;(2)MVF参数:对照组与吸毒组各组间随各组心功能逐渐增加E/A未见逐级递减关系,分析原因吸毒组B、C、D组E/A三类构成比不同(>1;<1;>2)分别为11/31/0、31/18/1、6/4/7;(3)PVF参数:吸毒组各组间B、C、D随各组心功能等级逐渐增加,S波速度、S/D数据递减,D波速度、AR、Adur数据递增。对照组A与吸毒B组之间除S波速度外均无明显差异;(4)组织多普勒成像参数:吸毒组各组间B、C、D组随各组心功能等级逐渐增加,e,e/a递减,a逐渐升高(P<0.05)。对照组A与吸毒B组之间无明显差异。结论结合组织多普勒成像二尖瓣及肺静脉血流频谱能够较为完整的体现出吸毒人员的左心室的舒张功能,并对所形成的功能障碍进行程度检测。Objective To evaluate the clinical value of combined evaluation of tissue left ventricular diastolic function by Doppler imaging in drug users. Methods 89 drug users were selected and divided into three groups and 59 healthy controls were selected as the study subjects. Tissue Doppler imaging and MVF, PVF were conducted;mitral valve E peak, A peak velocity and velocity ratio（E/A）; mitral valve E peak deceleration time DT; pulmonary vein contraction wave, diastolic wave velocity（S, D）; ratio of pulmonary vein contraction wave velocity to diastolic wave velocity （S/D）; pulmonary venous atrial contraction wave velocity （AR） and duration （Adur） were measured. Results （1）The younger the age of using drug and the longer the time of drug use, and the worse the left ventricular diastolic function. The left ventricular wall was thickening, and the left atrium and the left ventricle were larger; （2） MVF parameters： There was no gradual decline in E/A along with the increasing cardiac function in the control group and drug use group. The compo- sition ratio of three types of E/A was different in drug use group B, C and（〉l; 〈1; 〉2）, 11/31/0, 31/18/1,6/4/7 respectively; （3）PVF parameters：The PVF parameters were gradually increasing along with the cardiac function in drug use group B, C, and D. S-wave velocity, and S/D were decreasing, and D-wave velocity, and AR, Adur were increasing.There was no significant difference between the control group A and the drug use group B except S-wave velocity; （4）The pa- rameters of tissue Doppler imaging：The parameters were gradually increasing along with the cardiac function in the drug use group B, C and D, and E and E/A were decreasing and A was gradually increasing（P〈0.05）. There was no significant difference between the control group A and the drug use group B. Conclusion Tissue Doppler imaging combined with mitral and pulmonary venous flow spectrum can comprehensively reflect the diastolic function of left ventricle in drug use

关 键 词：组织多普勒成像 二尖瓣血流 肺静脉血流 左心室舒张功能 

分 类 号：R540.4[医药卫生—心血管疾病]