加味益气丸联合驻春胶囊预防骨质疏松性椎体压缩骨折PKP后再骨折效果观察  

Effect of Jiawei Yiqi Pill Combined with Zhuchun Capsule on Refracture after PKP for Osteoporotic Vertebral Compression Fractures

作　　者：黄勇[1] 周英杰[2] 柴旭斌[2] 杨晓姣[2] 罗金鑫 HUANG Yong ZHOU Yingjie CHAI Xubin YANG Xiaojiao LUO Jinxin(Graduate School of Hunan University of Chinese Medicine,Changsha 410208,China No.2 Department of Spine in Luoyang Orthopedic Hospital of Henan Province,Luoyang 471002,China)

机构地区：[1]湖南中医药大学研究生院,湖南长沙410208 [2]河南省洛阳正骨医院脊柱外二科,河南洛阳471002

出　　处：《山东中医杂志》2017年第5期368-370,共3页Shandong Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局国家中医临床研究基地业务建设科研专项课题(编号:JDZX2015082)

摘　　要：目的 :观察加味益气丸联合驻春胶囊预防骨质疏松性椎体压缩骨折(OVCFs)椎体后凸成形术(PKP)后再骨折的效果。方法:87例OVCFs患者按治疗方法分为A、B两组。A组口服加味益气丸与驻春胶囊,B组口服碳酸钙D3片,两组均治疗6个月。比较两组术前、术后1年骨密度变化及再骨折发生率。结果:两组术后1年骨密度值均升高,与术前比较,差异有统计学意义(P<0.05)。术后1年A组骨密度改善优于B组,差异有统计学意义(P<0.05)。术后1年邻近椎体再骨折率A组14.2%,B组21.1%,两组比较差异有统计学意义(P<0.05)。结论:PKP术后口服加味益气丸联合驻春胶囊,可提高骨质疏松患者骨密度,一定程度上可预防再次骨折。Objective：To observe the effect of Jiawei Yiqi pill combined with Zhuchun capsule on preventing refracture after percutaneous kyphoplasty （PKP） for osteoporotic vertebral compression fractures （OVCFs）. Methods：A total of 87 cases of OVCFs patients were divided into group A and group B according to the treatment methods they choose. Patients in group A were given Jiawei Yiqi pill combined with Zhuchun capsule for oral administration. Patients in group B were given calcium carbonate D3 for oral administration. Both the two groups were treated for 6 months. The bone mineral density and the refracture rate of the two groups before treatment and 1 year after the PKP were compared respectively. Results：One year after the PKP,the bone mineral density value of the two groups were increased,which were statistically different from those before the PKP（P〈0.05）. The improvement of bone mineral density of group A was better than that of group B,with statistical significance（P〈0.05）. One year after the PKP,the refracture rate of group A was 14.4% and the group B was 21.1%. There was a statistical significance between the two groups（P〈0.05）. Conclusion：After the PKP,Jiawei Yiqi pill combined with Zhuchun capsule can increase the bone mineral density of patients with osteoporosis and prevent refracture in a certain extent.

关 键 词：加味益气丸 驻春胶囊 骨质疏松 椎体压缩骨折 骨密度 

分 类 号：R274.1[医药卫生—中医骨伤科学]