1例慢性肾功能不全患者个体化抗栓药物治疗实践  

Individualized antithrombotic therapy on one patient with chronic renal insufficiency

作　　者：党翔吉 周玲[2] 王艺璇[3] 曾露[4] DANG Xiangji ZHOU Lin WANG Yixuan ZENG Lu(College of Pharmacy Lanzhou University Second Hospital, Lanzhou 730000, Gansu, China College of Phar- macy Suzhou University First Hospital, Suzhou 215006, Jiangsu, China College of Pharmacy Sun Yat-Sen University, Guangzhou 510006, Guangdong , China College of Pharmacy Tongfi Hospital, Tongfi Medical College Huazhong University of Science and Technology, Wuhan 430030, Hubei, China)

机构地区：[1]兰州大学第二医院药学中心 [2]苏州大学第一附属医院药学部 [3]中山大学药学院 [4]华中科技大学同济医学院附属同济医院

出　　处：《中国临床药理学与治疗学》2017年第4期477-480,共4页Chinese Journal of Clinical Pharmacology and Therapeutics

摘　　要：目的:探讨临床药师在慢性肾功能不全患者个体化应用抗栓药物治疗中的作用。方法:回顾性分析临床药师参与1例慢性肾功能不全患者个体化抗栓药物治疗的案例。结果:临床药师依据阿司匹林及依诺肝素药动学及药效学特征分析患者慢性肾衰竭及皮肤血肿形成原因,参与抗血栓治疗方案的调整,并为患者提供药学监护和用药教育。结论:以关注特殊人群个体化用药,保证临床疗效,避免不良反应发生,保证患者用药合理、安全、有效、经济,可作为临床药师药学服务的切入点。AIM： To evaluate the role of clini- cal pharmacist in individualized antithrombotic ther- apy on patients with chronic renal insufficiency. METHODS： To review clinical pharmacist partici- pating antithrombotic therapy on one patient with chronic renal insufficiency. RESULTS： Clinical pharmacist analyzed the causes of chronic renal failure and skin hematoma formation by pharmacokinetic and pharmacodynamic characteristics of aspirin and enoxaparin, participated the adjustment of an- tithrombotic therapy and implemented pharmaceutical care and pharmaceutical edueation for the patie- nts. CONCLUSION： Clinical pharmacist focuses on individualized medication of special crowd which could be the entry points for pharmaceutical care, avoid adverse reactions and ensure the reasonable, safety, effec, and economy of drug in patients.

关 键 词：慢性肾功能不全 阿司匹林 皮肤血肿 依诺肝素 临床药师 个体化用药 

分 类 号：R972[医药卫生—药品]