基于ICP-OES/MS技术的白矾及其伪品铵明矾的无机元素差异性分析  

Differences of Inorganic Elements Between Alumen and Its Counterfeit Ammonium Alum Based on ICP-OES/MS Technique

作　　者：乔婷婷[1] 刘圣金[1] 林瑞超[2] 郝薇[1] 房方[1] 吴超颖 吴德康[1] QIAO Ting-ting LIU Sheng-jin LIN Rui-chao HAO Wei FANG Fang WU Chao-ying WU De-kang(Nanjing University of Chinese Medicine, Nanjing 210023, China Beijing University of Chinese Medicine, Beijing 100029, China)

机构地区：[1]南京中医药大学,江苏南京210023 [2]北京中医药大学,北京100029

出　　处：《中药材》2016年第11期2462-2468,共7页Journal of Chinese Medicinal Materials

基　　金：2015年度中医药行业专项(2015468004-2-1);江苏高校优势学科建设工程资助项目(二期);江苏高校品牌专业建设工程资助项(PPZY2015A070)

摘　　要：目的:从无机元素角度分析白矾及其伪品铵明矾的差异,为白矾药材的质量控制提供参考依据。方法:应用电感耦合等离子体原子发射光谱(ICP-OES)和电感耦合等离子体质谱(ICP-MS)法测定白矾和铵明矾中24种无机元素的含量,采用SPSS 16.0软件对数据进行聚类分析,以SIMCA-P 13.0软件配合t检验及秩和检验对差异性无机元素进行识别,并建立白矾和铵明矾的无机元素特征谱。结果:白矾主要含K、Al等元素,铵明矾主要含Al、Fe等元素;白矾中微量元素除Cr外含量均相对较低,铵明矾中Mn、Ti、Ga含量较高,其次是Cr、Sr、V。聚类分析将19个样品聚类为白矾和铵明矾两大类。共筛选出18种差异性显著(P<0.05)的无机元素,分别为Be、Mg、Al、K、Ca、Ti、V、Mn、Fe、Co、Ni、Cu、Zn、Ga、As、Sn、Tl、Pb。建立了白矾、铵明矾含22种无机元素的特征谱。结论:该分析方法可用于白矾药材的质量控制。Objective：To evaluate the quality of Alumen by investigating the element differences between Alumen and its counterfeit Ammonium alum.Methods：The contents of 24 inorganic elements both in Alumen and Ammonium alum were determined by means of ICP-OES and ICP-MS,SPSS 16.0 was used for cluster analysis（CA） while SIMCA-P 13.0 with t-test and Rank-Sum test to identify the difference of inorganic elements.The characteristic spectrum of the inorganic elements of Alumen and Ammonium alum were established.Results：The contents of K and Al were the highest in Alumen while the content of Al and Fe was the highest in Ammonium alum;Trace elements in Alumen were relatively low except Cr,the value of Mn,Ti and Ga in Ammonium alum was higher,followed by Cr,Sr and V.The CA put the 19 samples together for two categories,one was Alumen and the other was Ammonium alum;18 inorganic elements significantly different（P〈0.05） were screened out,they were Be,Mg,Al,K,Ca,Ti,V,Mn,Fe,Co,Ni,Cu,Zn,Ga,As,Sn,Tl and Pb.Characteristic spectrum of 22 inorganic elements in Alumen and Ammonium alum were established.Conclusion：This method can be used to evaluate the quality of Alumen.

关 键 词：矿物药 白矾 铵明矾 ICP-OES ICP-MS 无机元素 质量评价 

分 类 号：R282.5[医药卫生—中药学]