维生素D与结缔组织疾病的心血管风险  

Vitamin D and Cardiovascular Risk in Connective Tissue Disease

作　　者：汪汉[1] 

机构地区：[1]成都市第三人民医院心血管病研究所,四川成都610031

出　　处：《心血管病学进展》2017年第3期347-349,共3页Advances in Cardiovascular Diseases

基　　金：国家自然科学基金(81300243);四川省医学科研青年创新课题(Q14013);四川省卫计委普及应用项目(16PJ042)

摘　　要：维生素D缺乏在结缔组织疾病中很常见,主要与疾病活动性相关,最近的研究发现维生素D可能与心血管的一些危险因素,如高脂血症、代谢综合征、胰岛素抵抗、炎症因子有一定关联。维生素D的免疫调节作用在其中有重要作用,然而,因果关系仍然难以确认,补充维生素D是否可以辅助管理结缔组织疾病的心血管危险因素目前不得而知。The deficiency of vitamin D is very common in connective tissue disease, and is mainly associated with disease activity. Recent studies have demonstrated that vitamin D may be associated with some cardiovascular risk factors, including hyperlipemia, metabolic syndrome,insulin resistance,and inflammation. Immune regulation has played an important role in these diseases, however, the causal relationship between these diseases and vitamin D remains unclear. Whether vitamin D replacement therapy is a promising adjunct in cardiovascular risk management among patients with connective tissue diseases is unknown.

关 键 词：维生素D 结缔组织疾病 类风湿性关节炎 系统性红斑狼疮 心血管危险 

分 类 号：R54[医药卫生—心血管疾病] R593.2[医药卫生—内科学]