多光谱眼底成像在糖尿病视网膜病变筛查中的应用  

Multiple Spectrum Imaging for Fundus Oculi in Application of Diabetic Retinopathy Screening

作　　者：仇长宇[1] 罗灵[1] 石圆圆[1] 闫洪欣[1] 童宗中[2] 胡莲娜[1] 高付林[1] 赵军[1] 郭惠玲[1] 宫玉波[1] 

机构地区：[1]解放军306医院眼科,北京100101 [2]四川省医学科学院四川省人民医院眼科,成都610072

出　　处：《解放军医药杂志》2017年第5期86-88,共3页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

基　　金：国家自然科学基金面上项目(B1271016;B1571055)

摘　　要：目的探讨多光谱眼底分层成像在糖尿病视网膜病变筛查方面的作用。方法按照诊断试验的研究方法,对解放军306医院2015年6—7月的13例糖尿病视网膜病变患者及9例对照者同时行多光谱眼底分层成像及眼底荧光血管造影检查,以眼底荧光血管造影检查的结果作为金标准,判断多光谱眼底分层成像对糖尿病视网膜病变的诊断价值。结果多光谱眼底分层成像诊断微血管瘤的灵敏度及特异度分别为84.0%及88.9%,约登指数为72.9%,阳性似然比及阴性似然比分别为7.57及0.18。阳性预测值及阴性预测值分别为91.3%及80.0%。结论多光谱眼底分层成像检查可以作为糖尿病视网膜病变的一种有效的筛查手段,具有较好的可靠性及诊断价值。Objective To investigate effect of multiple spectrum imaging （MSI） for fundus oculi in diabetic retinopathy （DR） screening. Methods MSI and fundus fluorescein angiography （FFA） were performed simultaneously for 13 DR patients and 9 controls from June to July 2015 according to study method of diagnostic test. FFA result was used as the golden criteria of DR to evaluate diagnostic value of MS1 for DR. Results The sensitivity and specificity of MSI in diagnosis of DR were 84.0% and 88.9% respectively; Youden index was 72.9% ; positive likelihood ratio and negative likelihood ratio were 7.57 and 0.18 respectively; positive predictive value and negative predictive value were 91.3 % and 80.0% respectively. Conclusion Multiple spectrum imaging can be used as an effective way to screen diabetic retinopathy, and it has good reliability and diagnostic value.

关 键 词：多光谱成像 眼底 糖尿病视网膜病变 荧光素血管造影术 

分 类 号：R587.26[医药卫生—内分泌]