炎症性肠病的药物治疗现状  

The research status of the drug therapy for inflammatory bowel disease

作　　者：卞莹莹[1] 王洁[2] 李安[2] 开国银 陆一鸣[2] 

机构地区：[1]上海师范大学生命与环境科学学院,上海200234 [2]第二军医大学药学院生化药学教研室,上海200433

出　　处：《药学实践杂志》2017年第3期197-200,228,共5页Journal of Pharmaceutical Practice

基　　金：国家自然科学基金资助项目(30500093;81274162);国家科技部"重大新药创制"专项(2009ZX09103-690);上海市科委生物医药领域科技支撑项目(16431904400);上海市教委科研创新项目(14ZZ077)

摘　　要：炎症性肠病(inflammatory bowel disease,IBD)目前是消化系统疾病的研究热点之一,主要包括溃疡性结肠炎(ulcerative colitis,UC)和克罗恩病(Crohn’s disease,CD),其发病机制尚未完全阐明,也尚无针对IBD的有效治疗药物。随着对IBD发病机制的深入研究,出现了一些新型药物和制剂。笔者就IBD及其药物治疗的研究现状作一简要综述。Research on the inflammatory bowel disease（IBD） is a hot topic in the field of digestive system disease.IBD mainly consists of ulcerative colitis（UC） and Crohn′s disease（CD）.The pathogenesis of IBD has not been fully understood.So far, there is no specific medication for IBD.A number of novel medicines and preparations have emerged with the research progress on the pathogenesis of IBD.The research status on IBD drug therapy is briefly reviewed in this paper.

关 键 词：炎症性肠病 溃疡性结肠炎 克罗恩病 药物治疗 

分 类 号：R975[医药卫生—药品]