镇痛药对骨折愈合影响的研究进展  

Research concerning the effect of analgesics on fracture healing

作　　者：王震[1] 张岩[1] 朱彦丞 邱旭升[1] 陈一心[1] 

机构地区：[1]南京医科大学鼓楼临床医学院,210008

出　　处：《中华创伤骨科杂志》2017年第5期457-460,共4页Chinese Journal of Orthopaedic Trauma

基　　金：基金项目：国家自然科学基金（81401793）;江苏省六大人才高峰项目（2012-WS-092）;南京市卫生局项目（ZKX12016,YKK13079）

摘　　要：镇痛药在骨折及骨折术后应用广泛。目前镇痛药主要有3类，分别为非甾体类抗炎药、中枢性镇痛药和局部麻醉药。近年来有研究显示，某些镇痛药在镇痛的同时对骨折愈合可能存在抑制作用，引起临床医生的关注。但也有研究者并不赞同这一结论。本文就镇痛药对骨折愈合影响的研究进展作一综述。Analgesics are widely used in fracture patients before and after operation. The analgesics frequently used include non-steroidal anti-inflammatory drugs, as well as central nerve and local medications. Recently, researches report that some analgesics may inhibit fracture healing, which has attracted much attention from orthopedic surgeons. However, there are researchers who hold opposite opinions. Accordingly, this paper reviews the progress in research concerning the effect of analgesics on fracture healing.

关 键 词：镇痛药 骨折愈合 非甾体类抗炎药 

分 类 号：R683[医药卫生—骨科学]