Synthesis of a novel C-branched polyhydroxylated cyclic nitrone  

作　　者：Qing-Kun Wu Yi-Xian Li Yue-Mei Jia Chu-Yi Yu 

机构地区：[1]Beijing National Laboratory for Molecular Science (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China [2]University of Chinese Academy of Sciences, Beijing 100049, China [3]National Engineering Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang 330022, China

出　　处：《Chinese Chemical Letters》2017年第4期909-912,共4页中国化学快报（英文版）

基　　金：Financial support from National Basic Research Program of China(No.2012CB822101);the National Natural Science Foundation of China(No.21272240);National Science and Technology Major Projects for "Major New Drugs Innovation and Development"(No.2013ZX09508104);National Engineering Research Center for Carbohydrate Synthesis of Jiangxi Normal University

摘　　要：A novel C-branched polyhydroxylated cyclic nitrone 25.which could be a valuable intermediate for the synthesis of C-branched pyrrolidine iminosugars,was synthesized starting from the commercially available i.-arabinose in 29.0%total yield.A novel C-branched polyhydroxylated cyclic nitrone 25.which could be a valuable intermediate for the synthesis of C-branched pyrrolidine iminosugars,was synthesized starting from the commercially available i.-arabinose in 29.0%total yield.

关 键 词：Cyclic nitrone Branched chain Iminosugars Azasugars Polyhydroxylated pyrrolidine 

分 类 号：TQ463.3[化学工程—制药化工]