妊娠期细小病毒B19感染状况分析  

Analysis of B19 virus infection during pregnancy in Shenyang

作　　者：张宁[1] 崔鑫[1] 魏威[1] 刘星池[1] 王梦醒[1] 于月新[1] 

机构地区：[1]中国人民解放军第二0二医院生殖医学中心,辽宁沈阳110003

出　　处：《中国实用妇科与产科杂志》2017年第6期632-635,共4页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：军队临床高新技术重大项目(2010gxjs003)

摘　　要：目的了解妊娠期细小病毒B19感染情况,为制订实施更为科学有效的产前筛查方法提供基础数据。方法选取2016年1月至5月在中国人民解放军第二0二医院进行产检的志愿者妇女455例,其中育龄妇女组69例,正常孕妇组223例,胎停孕妇组74例,胎儿异常流产或引产组89例。将各组资料与国内外相关研究进行比较。收集各组血清标本进行B19 Ig G、Ig M抗体测定。结果与育龄妇女组比较,其余各组B19 Ig G、Ig M阳性率差异无统计学意义(P>0.05)。本地区育龄妇女B19 Ig G、Ig M阳性率均低于国内外相关研究结果(P<0.05)。结论建议对高危人群在孕前评估对B19的免疫力,对易感人群在孕期进行B19病毒筛查。Objective To investigate the situation of B19 virus infection during pregnancy in Shenyang, and provide basic data for scientific and effective prenatal screening.Methods We selected 455 volunteers from January 2016 to May 2016 in No.202 Hospital of PLA.Tbey were assigned into four groups： the group of women at childbearing age （control group=69）, the group of normal pregnancy （n=223）, the group of embryo stop （n=74）, the group of miscarriage or abortion （n=89）.Serum samples were collected for B19 IgG/IgM detection, which were compared with those data abroad.Results Compared with the control, the difference in positive rate of B 19 virus infection in each experimental group were not significant （P〉O.O5）.The positive rate of B19 IgG/IgM of the control was lower than those of other areas in China and abroad （P〈0.05）.Conclusion It is suggested that high risk population in Shenyang should be evaluated before pregnancy on immunity to B 19, and the susceptible population should be screened for B 19 during pregnancy.

关 键 词：B19病毒 免疫球蛋白G 免疫球蛋白M 

分 类 号：R714.62[医药卫生—妇产科学]