阿托伐他汀钙联合曲美他嗪治疗冠心病的效果观察  

Effect of atorvastatin calcium combined with trimetazidine on coronary heart disease

作　　者：卫娇娜[1] 王永进 王众国[2] 高宏波[1] WEI Jiao-na WANG Yong-jin WANG Zhong-guo GAO Hong-bo(the 1st Ward the 2nd Ward, Department of Cardiology, the People＇s Hospital of Hanzhong, Hanzhong 723000, China)

机构地区：[1]陕西省汉中市人民医院心血管内科一病区,陕西汉中723000 [2]陕西省汉中市人民医院心血管内科二病区,陕西汉中723000

出　　处：《临床医学研究与实践》2017年第14期38-39,共2页Clinical Research and Practice

摘　　要：目的探讨曲美他嗪与阿托伐他汀钙联用治疗冠心病的临床效果。方法选择我院收治并确诊为冠心病的患者90例,随机将其分为对照组和治疗组,每组45例。对照组患者单纯采用阿托伐他汀钙治疗,治疗组患者采用曲美他嗪与阿托伐他汀钙两种药物联合治疗。对比两组患者治疗前、后的CRP水平、冠心病药物治疗效果、心电图表现恢复正常时间和冠心病药物治疗总时间、不良反应发生情况。结果治疗后,治疗组患者CRP水平的改善幅度明显大于对照组(P<0.05);且治疗组患者冠心病药物治疗效果明显优于对照组(P<0.05);治疗组患者心电图表现恢复正常时间和冠心病药物治疗总时间明显短于对照组(P<0.05);治疗组患者用药导致的不良反应明显少于对照组(P<0.05)。结论曲美他嗪与阿托伐他汀钙两种药物联合应用,对冠心病患者实施治疗的临床效果非常明显。Objective To study the Effect of atorvastatin calcium combined with trimetazidine on coronary heart disease. Methods Ninety cases of patients diagnosed with coronary heart disease in our hospital were selected and randomly divided into control group and treatment group, with 45 cases in each group. The control group was treated with atorvastatin calcium alone, while the treatment group was treated with trimetazidine and atorvastatin calcium. The CRP levels, coronary heart disease drug treatment effect, ECG performance returned to normal time and total time of coronary heart disease drug treatment, adverse reactions of the two groups before and after treatment were compared. Results After treatment, the improvement of CRP in the treatment group was significantly higher than that in the control group （P〈0.05）; the coronary heart disease drug treatment effect in the treatment group was significantly better than that in the control group （P〈0.05）; the ECG performance returned to normal time and total time in the treatment group were shorter than those in the control group （P〈0.05）; the adverse reactions caused by medication in the treatment group were significantly less than those in the control group （P〈0.05）. Conclusion Atorvastatin calcium combined with trimetazidine has obvious curative effect on patients with coronary heart disease.

关 键 词：曲美他嗪 阿托伐他汀钙 冠心病 

分 类 号：R541.4[医药卫生—心血管疾病]