预激性心肌病与左心室功能不全  

Preexcitation Cardiomyopathy and Left Ventricular Dysfunction

作　　者：廖斌[1] 陈椿[1] 

机构地区：[1]南京医科大学第一附属医院心内科,南京210029

出　　处：《医学综述》2017年第10期1962-1966,共5页Medical Recapitulate

摘　　要：预激性心肌病病理变化机制尚不明确,由旁路引起的同步化障碍运动是可能的原因之一。B型预激综合征可引起类似完全性左束支传导阻滞和右心室起搏模式的异常心脏电机械模式,导致间隔和游离壁的同步化障碍运动,出现游离壁相对间隔部滞后的现象,最后导致左心室功能不全及扩张型心肌病的发生。预激的类型、负荷、程度等可能是预激性心肌病的影响因素。对于有可能出现预激性心肌病的患者,可能需要更积极地抑制旁路治疗来预防预激性心肌病的发生。The pathophysiological mechanism of preexcitation cardiomyopathy is not clear yet. The synchronization caused by accessory atrioventricular pathways may be one of the reasons. Type B Wolff-Parkinson-White syndrome can cause abnomal electromechanical patterns similar to right ventricular pacing and LBBB, induces early interventricular septal motion and delayed activation of free wall. This dyskinetic segment will lead to left ventricular dysfunction and adverse remodeling with progressive dilation. The type of Wolff-Parkinson-White syndrome, the burden and degree of ventricular preexcitation may be the factors influencing the occurrence of preexcitation cardiomyopathy. More active treatment of bypass inhibition might be needed for patients with the risk factors to prevent preexcitation cardiomyopathy.

关 键 词：预激 同步化 心功能不全 

分 类 号：R541.77[医药卫生—心血管疾病]