从虚喘论治特发性肺纤维化的思路与方法  

Thoughts and Methods in Treating Idiopathic Pulmonary Fibrosis as Deficient Dyspnea

作　　者：任培中 高金柱[1] 樊茂蓉[1] 袁沙沙[1] 苗青[1] 

机构地区：[1]中国中医科学院西苑医院,北京市100091

出　　处：《中医杂志》2017年第11期929-932,共4页Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(30901948);北京市自然科学基金(7162168);北京市科技计划(Z131107002213053)

摘　　要：特发性肺纤维化与中医学"虚喘"具有密切相关性,二者病因病机颇为相合,因此,提出将之归属于虚喘范畴论治。认为气虚是虚喘的原发病因,肾精亏虚是虚喘的关键病机,二者贯穿疾病发生发展的整个过程,故而特发性肺纤维化的治疗亦当以虚喘的主要治法即补气益肾为主。贞元饮是张景岳治疗虚喘的重要方剂,其主要作用是补肾益精,加入人参、黄芪共奏补气益肾之功,用于治疗特发性肺纤维化可取得一定疗效。Idiopathic pulmonary fibrosis （IPF） closely relates to deficient dyspnea in Chinese medicine. The causes and pathogenesis of both diseases matched each other. IPF could be treated as deficient dyspnea. The authors hold that Qi deficiency is the primary cause of deficient dyspnea, and deficiency of kidney essence is the key patho- genesis. Deficiency of Qi and kidney essence exists throughout the process of disease development. Therefore treat- ment of IPF should be mainly invigorating Qi and benefiting kidney which is the main therapy of deficient dyspnea. Zhenyuan Yin （贞元饮） is an important prescription of ZHANG Jingyue to treat deficient dyspnea. The main effect is invigorating kidney and benefiting essence. Adding Renshen [ Radix Ginseng, 人参 ] and Huangqi [ Astragalus membranaceus, 黄芪 ] could invigorate Qi and benefit kidney, which is effective in treating IPF.

关 键 词：特发性肺纤维化 虚喘 气虚 肾精亏虚 贞元饮 

分 类 号：R259[医药卫生—中西医结合]