轻度认知障碍与抑郁情绪的独立关系  

Independent relationship between mild cognitive impairment and depression

作　　者：史亚楠[1] 方柳絮 杨莉莉[1] 孙秋华[1] 

机构地区：[1]浙江中医药大学,浙江杭州310053

出　　处：《现代预防医学》2017年第11期2014-2017,2022,共5页Modern Preventive Medicine

摘　　要：目的探讨轻度认知障碍与抑郁情绪之间的独立关系。方法数据收集采用面对面交谈。采用蒙特利尔认知评估量表筛查轻度认知障碍患者、老年抑郁量表评估抑郁情绪,控制影响抑郁情绪的社会人口学资料、健康状况、日常功能和主观记忆下降等混杂因素,通过Logistic回归分析抑郁症状与轻度认知障碍之间的独立关系。结果轻度认知障碍患者抑郁情绪的发生率为31.82%,校正混杂因素之后,抑郁情绪和轻度认知障碍之间仍然存在明显相关关系(OR=5.834;95%CI 2.230-15.262;P<0.001)。结论相对于认知正常老年人,老年MCI患者有更高的可能性出现抑郁情绪,医务人员应该意识到轻度认知障碍患者抑郁情绪的程度和危害,积极采取行动评估和治疗抑郁情绪。Objective To examine the independent relationship between mild cognitive impairment （MCI） and the presence of depressive symptoms. Methods Data were obtained through face - to - face interview. MCI subjects were screened by the Montreal Cognitive Assessment and depressive symptoms were measured by the Geriatric Depression Scale. The relationship between the presence of depressive symptoms and MCI was analyzed by logistic regression while controlling the social - demographic factors,health conditions, functional performance and subjective memory complaint. Results The prevalence of depressive symptoms among Chinese elders with MCI was 31.82%. After adjusting confounding factors, depressive symptoms was found to be significantly associated with MCI （ odds ratio = 5. 834,95% confidence interval 2. 230,15. 262, P 〈 0. 001 ）. Conclusion MCI patients have a higher likelihood of representing depressive symptoms. Medical workers should be aware of the extent and impact of depressive symptoms in MCI and take active steps in evaluating and treatment of depressive symptoms.

关 键 词：轻度认知障碍 抑郁 独立关系 

分 类 号：R193[医药卫生—卫生事业管理]