妊娠期干燥综合征管理  

Management of Sj?gren's syndrome during pregnancy

作　　者：张舸[1] 闫冰[1] 刘湘源[2] 

机构地区：[1]北京市海淀医院北京大学第三医院海淀院区,北京100080 [2]北京大学第三医院风湿免疫科,北京100191

出　　处：《中国实用内科杂志》2017年第6期506-508,共3页Chinese Journal of Practical Internal Medicine

摘　　要：干燥综合征是一种系统性自身免疫性疾病。干燥综合征不影响女性患者的生育能力,但其与妊娠之间相互影响,影响胎儿宫内的生长发育,影响妊娠结局,增加自然流产率和早产率。妊娠期间干燥综合征的治疗目的主要是终止或抑制患者体内的异常免疫反应,保证胎儿宫内正常生长发育,预防妊娠期并发症及新生儿并发症。治疗主要包括对症治疗和系统性治疗,系统性治疗又包括糖皮质激素和免疫抑制剂等。文章就干燥综合征的概述、干燥综合征与妊娠的相互影响、干燥综合征的治疗、孕期监测和妊娠时机等方面进行介绍。Sj6gren＇s syndrome is a systemic autoimmune disease. It does not affect the fertility of female patients, but its interaction with pregnancy affects the growth and development of fetal intrauterine and affects the outcome of pregnancy, increasing the rate of spontaneous abortion and premature delivery. The purpose of treatment and Sjogren＇s syndrome during pregnancy is to terminate or inhibit the abnormal immune response in patients, to ensure normal fetal growth and development, and to prevent the complications during pregnancy and neonatal complications. Treatment mainly includes symptomatic treatment and systemic treatment, and systemic treatment mainly includes glucocorticoids and immunosuppressive agents. In this paper, we make a review the an overview of Sjogren＇s syndrome, the interaction of Sjogren＇s syndrome with pregnancy, the treatment of Sjogren＇s syndrome, pregnancy monitoring, timing of pregnancy and so on.

关 键 词：干燥综合征 妊娠 管理 

分 类 号：R593.2[医药卫生—内科学]