慢性心力衰竭患者血尿酸与血浆脑钠肽水平变化的分析  

Analysis of serum uric acid and plasma brain natriuretic peptide levels of patients with chronic heart failure

作　　者：潘立敏[1] 

机构地区：[1]广东省佛山市南海区第七人民医院,广东佛山528200

出　　处：《中国医药科学》2017年第7期204-206,共3页China Medicine And Pharmacy

摘　　要：目的探讨慢性心力衰竭患者血尿酸与血浆脑钠肽水平变化规律。方法收集2016年9月~2017年1月在我院住院治疗的慢性心力衰竭患者100例为观察组,选择同期来我院进行体检的30例健康就诊者为对照组,比较两组血尿酸与血浆脑钠肽水平变化情况。结果随着患者心脏功能级别的增大,患者血尿酸和血浆脑钠肽水平也会随之升高,差异有统计学意义(P<0.05),血浆脑钠肽水平和左心室收缩末期内径、左心室舒张末期内径表现为正相关(r1=0.75,r2=0.80),和左心室射血分数呈负相关(r=-0.71)。结论慢性心力衰竭患者血尿酸、脑钠肽水平升高,且会随着心功能分级的增加而逐渐提升。Objective To evaluate the change rule of serum uric acid and plasma brain natriuretic peptide levels of patients with chronic heart failure. Methods 100 cases of patients with chronic heart failure cured in our hospital from September 2016 to January 2017 were selected as the observation group.At the same time,30 cases of medical health patients were selected as control group.The blood uric acid and the change of the level of plasma sodium peptide of the two groups were compared. Results The level of serum uric acid and plasma brain natriuretic peptide （BNP） would increase with the increase of cardiac function.The difference was significant,and it had statistical significance （P 〈 0.05）.The plasma level of brain showed positive correlation with left ventricular end systolic diameter,left ventricular end-diastolic diameter （r1=0.75,r2=0.80）,and it showed negative correlation with left ventricular ejection fraction （r=-0.71）. Conclusion Serum uric acid and plasma brain natriuretic peptide levels will increase in patients with cardiac function.

关 键 词：慢性心力衰竭患者 血尿酸 血浆脑钠肽水平 变化 

分 类 号：R541.6[医药卫生—心血管疾病]