急性大脑中动脉闭塞患者磁共振高信号血管征形成的影响因素  

Analysis on the factors affecting formation of hyperintense vessel sign of acute middle cerebral artery occlusion on FLAIR MRI

作　　者：蒋海昌 黄显军[1] 宋建龙[1] 周志明[1] 

机构地区：[1]皖南医学院第一附属医院弋矶山医院神经内科,安徽芜湖241001

出　　处：《皖南医学院学报》2017年第3期217-220,共4页Journal of Wannan Medical College

摘　　要：目的:探讨急性大脑中动脉闭塞患者头颅磁共振液体衰减反转恢复序列(FLAIR)高信号血管征(HVS)的影响因素。方法:选择2014年7月~2016年6月于弋矶山医院神经内科住院治疗的急性大脑中动脉闭塞患者共75例,收集所有患者基线资料、头颅磁共振(需包括DWI、FLAIR+MRA)影像及血液学检查结果,根据大脑中动脉闭塞区域远端HVS的数量分为两组,比较两组间基线资料及影响HVS形成的临床危险因素。结果:75例患者中,梗死区域远端HVS<2分组共44例(58.67%)、HVS 2分组共31例(41.33%)。单因素分析显示两组间糖尿病、胆固醇、甘油三酯存在显著差异(P<0.05);多因素Logistic回归分析表明糖尿病是影响大脑中动脉梗死区域远端HVS形成的独立危险因素(OR=5.46,95%CI 1.351~22.069,P<0.05)。结论:糖尿病是影响急性大脑中动脉闭塞患者头颅磁共振T2FLAIR序列高信号血管征形成的独立危险因素。Objective：To investigate the clinical factors affecting the formation of hyperintense vessel sign（HVS） on MR imaging（MRI） in fluid-attenuated inversion recovery（FLAIR） in patients with acute middle cerebral artery occlusion.Methods： A total of 75 patients with acute cerebral artery occlusion admitted to the Department of Neurology of our hospital were enrolled from July 2014 to June 2016,and the case data,including baseline data,cerebral MRI（FLAIR＋MRA,DWI）findings as well as blood biochemical tests,were collected.Then the cases were divided into two groups according to the number of middle cerebral artery occlusion at distal HVS for comparing the baseline data and the risk factors affecting HVS formation.Results：In the 75 cases,44（58.67%） were scored lower than 2 and 31（41.33%） were equal to 2 by HVS distal to the arterial occlusion.Single factor analysis showed that diabetes and levels of cholesterol and triglyceride were significantly different between groups（P〈0.05）,and multi-factor Logistic regression analysis indicated that diabetes mellitus was the independent risk factor for the formation of distal HVS（OR =5.46,95% CI 1.351-22.069,P〈 0.05）.Conclusion：Diabetes mellitus is an independent risk factor for the formation of HVS on MRI at FLAIR in patients with acute middle cerebral artery occlusion.

关 键 词：急性脑梗死 大脑中动脉 高信号血管征 危险因素 

分 类 号：R445.2[医药卫生—影像医学与核医学]