扩散张量成像在轻度脊髓型颈椎病诊断中的价值  

Diagnostic value of diffusion tensor imaging in mild cervical spondylotic myelopathy

作　　者：丁俊[1] 陈基明[1] 

机构地区：[1]皖南医学院第一附属医院弋矶山医院医学影像中心,安徽芜湖241001

出　　处：《皖南医学院学报》2017年第3期270-273,共4页Journal of Wannan Medical College

基　　金：安徽高校省级自然科学研究项目(KJ2014A275)

摘　　要：目的:探讨扩散张量成像(DTI)对轻度脊髓型颈椎病的应用价值。方法:选择40例脊髓型颈椎病(CSM)患者及20例健康志愿者进行常规MRI及DTI扫描。CSM患者按照T2WI图像颈髓受压信号差异分为A组(轻度组,颈髓内信号无异常)及B组(重度组,颈髓内出现高信号),健康志愿者为C组,将感兴趣区(ROI)置于颈髓白质前索、后索、左前侧索、左后侧索、右前侧索、右后侧索6个部位后处理数据,采用方差检验比较3组颈髓不同部位表观扩散系数(ADC)及各向异性分数(FA)之间的差异。结果:3组间各部位ADC值比较差异有统计学意义(P<0.05),组间多重比较,B组各部位ADC值均高于A组和C组(P<0.05);A组各部位ADC值高于C组(P<0.05);3组间各部位FA值比较差异有统计学意义(P<0.05),组间多重比较,B组各部位FA值均低于A组和C组(P<0.05);A组各部位FA值低于C组(P<0.05)。结论:DTI可以定量分析轻度脊髓型颈椎病颈髓内部结构微细变化,更好地辅助临床医生早期诊疗轻度脊髓型颈椎病。Objective：To assess the clinical value of diffusion tensor imaging（DTI） as a quantitative tool in diagnosis of mild cervical spondylotic myelopathy（CSM）.Methods：Forty patients with CSM and another 20 healthy volunteers were recruited,and subjected to conventional magnetic resonance（MR） scans and DTI.CSM patients were divided into group A（mild lesion without abnormal signal at the cervical spinal cord） and group B（mild lesion with high signal at the spinal cord） by the signal change on T2 weighed imaging at compressed cervical spinal segment,and the healthy volunteers were included in group C.Quantitative data were obtained at the regions of interest（ROI）,including anterior funiculus,dorsal funiculus,left anterior lateral funiculus,left posterior lateral funiculus,and right anterior and posterior lateral funiculi.Variance test was performed to compare apparent diffusion coefficient（ADC） and fractional anisotropy（FA） in diverse cervical involvement region among the three groups.Results：ADC and FA were significantly different in three groups（P〈0.05）.Comparison within groups indicated that group B had higher ADC value and lower FA value than group A and C（P〈0.05）,and ADC was higher and FA was lower in group A compared to group C（P〈0.05）.Conclusion： DTI can be a quantitative tool in demonstrating the microstructural integrity of mild CSM,which may better assist clinicians in early diagnosis and treatment of this entity.

关 键 词：脊髓型颈椎病 扩散张量成像 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学]