心脏死亡器官捐献供者器官功能维护108例经验总结  

Experience summary on maintenance of organ function in donation after cardiac death donors:a report of 108 cases

作　　者：许传屾[1] 李志强[1] 郭源[1] 范宁[1] 王淑贤[1] 王新[1] 王建红[1] 付晓悦[1] 关鸽[1] 吴晓冬[1] 臧运金[1] 

机构地区：[1]青岛大学附属医院器官移植中心,266003

出　　处：《中华移植杂志（电子版）》2017年第1期28-31,共4页Chinese Journal of Transplantation(Electronic Edition)

基　　金：山东省医药卫生科技发展计划项目(2016WS0272)

摘　　要：目的探讨公民心脏死亡器官捐献(DCD)的维护措施,提高DCD供器官数量和质量。方法 2015年5月至2016年5月期间,青岛大学附属医院器官捐献ICU(D-ICU)共成功实施108例DCD。通过完善的组织体系和多中心协作方式、规范化和标准化的操作流程、制定个体化器官功能维护方案以及本中心创新措施,以提高器官捐献率。结果成功实施DCD108例,共获取大器官338个,其中肝脏95个(包含5例在体劈离式供肝)、肾脏212个、心脏16个、肺脏15个,大器官获取比1∶3.13。根据潜在捐献者病情,使用持续血液透析滤过、体外膜肺氧合、连续性肾脏替代治疗等方法维护器官功能,扩大捐献器官的使用率。结论通过规范化、标准化的器官功能维护措施,有利于提高器官捐献率及获取率,提高获取器官质量。Objective To explore the maintenance measures for the organs from donation after cardiac death （DCD） so as to improve the quantity and quality of donated organs. Methods Clinical data was collected from 110 potential organ donors who were admitted to the donor-ICU （D-ICU） of the Affiliated Hospital of Qingdao University during May 2015 and May 2016. Efforts were made to improve the organ donation rate by the measures including organization system optimization, multi-center collaboration, process normalization and standardization, formulation of individual plan on maintenance of organ function and adoption innovative measures from our organ transplantation center. Results A total of 338 major organs were procured from 108 donors undergoing DCD, including 95 livers （5 cases were used for split liver transplantation）, 212 kidneys, 16 hearts and 15 lungs with a ratio of 3. 13 （338/108）. The utilization rate of donor organs was improved by application of persistent hemodiafiltration, extracorporeal membrane oxygenation and continuous renal replacement therapy according to the potential organ donors＇s condition. Conclusion Normative and standardized organ function maintenance measures are favorable for improving organ donation rate, organ procurement rate, and quality of procured organs.

关 键 词：心脏死亡器官捐献 潜在捐献者 器官功能维护 

分 类 号：R617[医药卫生—外科学]