适宜水碘含量上限阈值的探讨  

Exploration on proper upper threshold of iodine content in drinking water

作　　者：路毓峰 吕胜敏[2] 刘华[3] 赵英录[4] 王玉春[5] 

机构地区：[1]石家庄市第五医院,河北050021 [2]河北省疾病预防控制中心 [3]沧州市疾病预防控制中心 [4]邢台市疾病预防控制中心 [5]衡水市疾病预防控制中心

出　　处：《中国地方病防治》2017年第2期131-133,共3页Chinese Journal of Control of Endemic Diseases

摘　　要：目的探讨适宜水碘含量的上限阈值。方法在河北省停供碘盐的5个市髙碘地区,选择水碘含量在20-310μg/L之间的12个村,采集尿样、水样和居民户食用盐,调查居民饮用水的碘含量和8-10岁儿童的尿碘含量之间的关系。结果 12个调查村水碘中位数在29.0-307.8μg/L之间,8-10岁儿童尿碘中位数在240.0-458.9μg/L之间。采用Spearman等级相关分析(R=0.951,P=0.000),儿童的尿碘中位数与其所在村的水碘中位数呈正相关。直线回归分析发现,儿童尿碘含量的变化中有88.9%与水碘含量的变化有关。线性回归方程为y=0.676x+225.6,当尿碘中位数为300μg/L时,水碘中位数为110μg/L。结论高碘地区水碘含量是影响儿童尿碘含量的主要因素,适宜水碘含量上限阈值为110μg/L。Objective To explore the proper upper threshold of iodine content in drinking water.Method Twelve villages with iodine content in drinking water ranged from 20 μg/L to 310 μg/L in the high iodine areas in 5 cities of Hebei province to investigate the relationship between iodine content in drinking water and in urine samples of children aged 8 to 10 years old.Results The median water iodine in the 12 villages ranged from 29.0 μg/L to 307.8 μg/L and the median urinary iodine content of children aged 8 to 10 years old varied from 240.0 μg/L to 458.9 μg/L.Children’s MUIC were correlated positively with the median water iodine in the 12 villages（ Spearman, R = 0.951,P = 0.000）.Analyzed by linear regression,approximately 88.9% of the variability in children’s median urinary iodine was associated with variability in the median water iodine（ P = 0.000）.The linear regression equation was as followed： y = 0.676x＋225.6.When y is 300 μg/L,the is 110 μg/L.Conclusion In high iodine areas,water iodine content is the main determinants of children’s urinary iodine content. The proper upper threshold of water iodine could be 110 μg/L.

关 键 词：水碘 尿碘 阈值 调查 

分 类 号：R591.1[医药卫生—内科学]