高血压病患者血压变异性与靶器官损伤关系的研究进展  

Advances of the relationship between blood pressure variability and target organ damage in patients with high blood pressure

作　　者：丁晓宇[1] 钱宗杰[1] DING Xiaoyu QIAN Zongjie(Department of Cardiology, Affiliated Hospital of Guilin Medical University, Guangxi Zhuang Autonomous Region, Guilin 541001, China)

机构地区：[1]桂林医学院附属医院心血管内科,广西桂林541001

出　　处：《中国医药导报》2017年第15期35-38,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81160489);广西自然科学基金项目(2012GXNSFAA053080);广西医疗卫生适宜技术研究项目(S201407-02);广西高校科学技术研究项目(YB2014283)

摘　　要：高血压病引起患者靶器官损伤证据充分,特别是与心血管系统有关联的靶器官。血压变异性因与靶器官损伤也有一定正相关关系,关注度明显增高。越来越多的证据表明,高血压病患者的血压变异性越大,靶器官损伤的程度越明显。所以,降低血压的变异性能够一定程度地降低靶器官损伤的风险。本文就血压变异的监测方法及血压变异性与靶器官损伤关系进行综述,以期最终通过降低血压变异性来降低高血压病患者的靶器官损伤率及临床伴随疾病的发生率。There is sufficient evidence that hypertension caused target organ damage, especially in the cardiovascular system. The damage degree of target organs is positively correlated with BP variability （BPV）. A growing body of evi- dences show that the more hypertension patient＇s BPV increased, the more serious target organ damaged, so it can re- duce the risk of target organ damage in some degree by reducing the BPV. This article reviews the literature about the methods of BPV monitoring and relationship between BPV and target organ damage, looks forward to reduce the target organ damage rate of the hypertension patients and the incidence of clinical diseases by reducing the BPV.

关 键 词：高血压病 血压变异性 动态血压监测 靶器官损伤 

分 类 号：R544.1[医药卫生—心血管疾病]