老年重症肺炎患者营养学相关检验指标的主成分分析  

Principal component analysis on nutritional status related clinical laboratory indexes in elderly patients with severe pneumonia

作　　者：熊波[1] 唐万平[1] 昝海峰[1] 颜晓玉[1] 曾强林[1] 周晖[1] XIONG Bo TANG Wan-ping ZAN Hai-feng YAN Xiao-yu ZENG Qiang-lin ZHOU Hui(Center for Pulmonary Vascular Disease ＆ Department of Respiratory Medicine,Affiliated Hospital of Chengdu Universi- ty,Sichuan Province,Chengdu 610081,China)

机构地区：[1]成都大学附属医院呼吸内科&肺血管病诊治中心,四川成都610081

出　　处：《中国当代医药》2017年第15期132-135,共4页China Modern Medicine

摘　　要：目的探讨老年重症肺炎患者临床营养学相关检验指标失衡的特征,分析其变化与患者死亡的关系。方法回顾性分析我院2013年7月~2015年6月收治的97例老年重症肺炎患者,根据患者是否死亡分为死亡组(38例)和存活组(59例),搜集患者的年龄、性别、病程、合并的基础疾病等一般资料及临床资料,并搜集营养学相关指标[血红蛋白(Hb)、红细胞比积(HCT)、总蛋白(TP)、白蛋白(Alb)、前白蛋白(PA)、血总胆固醇(CHO)、血肌酐(SCr)],应用主成分分析提取综合预测因子对各指标进行综合评价。结果两组患者的前4个公因子累计方差贡献率>85%,代表各因子的贡献率分别为λ_1=40.749、λ_2=21.216、λ_3=14.823、λ_4=10.098、λ_5=6.195、λ_6=3.978、λ_7=2.941,各主成分重要性得分如下:Hb为0.140,HCT为0.247,TP为0.167,Alb为0.179,SCr为0.031,CHO为0.159,PA为0.079。结论老年重症肺炎患者临床营养学相关检验指标对死亡患者与生存患者影响具有差异,其检测对辅助评估患者死亡风险具有潜在作用。Objective To explore the imbalance features of nutritional related clinical laboratory indexes in elderly patients with severe pneumonia （SP）,and to analyze relationship between such change and mortality.Methods 97 elderly patients with severe pneumonia from July 2013 to June 2015 in our hospital were retrospectively analyzed,according to whether patients died,all patients were divided into the death group （38 cases） and the survival group （59 cases）.The general data of patients＇age,gender,course of disease,combined with basic diseases and clinical data were collected,and related nutrition indicators of hemoglobin（Hb）,hematocrit （HCT）,total protein （TP）,albumin （Alb）,prealbumin （PA）,serum total cholesterol （CHO）,serum creatinine （SCr） were selected,principal component analysis was used to extract comprehensive predictive factors,and comprehensive evaluation of each index was made.Results The cumulative variance contribution rate of the first 4 common factors in the two groups was more than 85%,and in the contribution rates of each factor, hi was 40.749,k2 was 21.216,k3 was 14.823,k4 was 10.098,k5 was 6.195,k6 was 3.978,k7 was 2.941.The principal component importance scores were as follows：Hb was 0.140,HCT was 0.247,TP was 0,167,Alb was 0.179,SCr was 0.031,CHO was 0.159,PA was 0.079.Conclusion The clinical nutrition related test indexes of elderly patients with severe pneumonia have different influence on the death patients and the survival patients,and their detection can play a potential role in auxiliary evaluation of the risk of death.

关 键 词：肺炎 危险因素 主成分分析法 

分 类 号：R446.1[医药卫生—诊断学]