3.0T高分辨率磁共振在基底动脉粥样斑块特征分析中的初步探讨  

Morphologic characteristics of atherosclerotic basilar arteries at 3.0T high-resolution MRI

作　　者：田霞[1] 刘崎[1] 陈录广[1] 彭雯佳[1] 张雪凤[1] 詹茜[1] 陆建平[1] 

机构地区：[1]第二军医大学附属长海医院影像科,上海200433

出　　处：《实用放射学杂志》2017年第6期519-523,共5页Journal of Practical Radiology

基　　金：全军医学科研“十二五”计划重点课题（BWS12J026）;上海市市级医院新兴前沿技术联合攻关项目（SHDC12013110）;国家自然科学基金面上项目（31470910）.

摘　　要：目的 探讨3.0T高分辨率磁共振在基底动脉（BA）粥样硬化的重构模式及斑块的分布特征。 方法 对90例经数字减影血管造影（DSA）确诊的动脉粥样硬化性BA中重度狭窄（50%-99%）患者进行分析。测定BA患者最狭窄层面的管腔面积、血管面积、参考管腔面积和参考血管面积；统计斑块在最狭窄层面的分布位置。比较阴性重构组及阳性重构组之间的定量及定性结果有无统计学差异，并统计最狭窄层面斑块的分布位置。 结果 本研究最终纳入51例患者，其中阳性重构患者占72.5%（37/51），阴性重构患者占27.5%（14/51）。相对于阴性重构组，阳性重构组具有较大的斑块面积斑块负重百分比以及较大的最大管壁厚度。在本研究中，BA斑块主要分布于腹侧壁。 结论 3.0T高分辨率磁共振对于BA狭窄重构模式及斑块分布特征的评估具有一定价值。Objective To explore the remodeling modes and the plaque distribution of atherosclerotic BA at 3.0T high-resolution MRI. Methods 90 symptomatic patients with atherosclerotic stenosis of BA on digital subtraction angiography （DSA） （50 0/00- 99-） were recruited consecutively. Luminal area, vessel area of maximal narrow sites and the reference sites were measured. The differences of involved imaging parameters between negative group and positive group were analyzed. Results 51 patients with required imaging quality were enrolled finally.Among the 51 patients,the rate of positive remodeling cases was 72.5 % （37/51） and negative remodeling took over 27.5 % （14/51）. Compared with the negative remodeling group, the positive remodeling group had greater plaque size, larger plaque burden percentage, and higher maximal wall thickness at maximal lumen narrowing sites. The plaques were mainly located at ventral wall of the vessel. Conclusion 3.0T high resolution MR imaging could be applied in assessing the remodeling modes and plaque distribution of BA stenosis.

关 键 词：动脉粥样硬化 基底动脉 磁共振成像 

分 类 号：R543[医药卫生—心血管疾病] R445.2[医药卫生—内科学]