兔肝脏3.0T MR多模态定量成像扫描技术探讨  

The technical investigation of 3.0T multi-modal quantitative MR imaging in rabbit liver

作　　者：岳丽娜[1] 高梅梅[1] 胡慧玲[1] 牛娟琴[1] 叶建军[1] 朱小花[1] 罗亚萍[1] 韩月东[1,2] 激扬[3] 

机构地区：[1]兰州军区兰州总医院影像科,甘肃兰州730050 [2]西安交通大学附属高新医院放射科,陕西西安710075 [3]西安医学院第一附属医院影像科,陕西西安710077

出　　处：《实用放射学杂志》2017年第6期644-647,共4页Journal of Practical Radiology

基　　金：陕西省自然科学基础研究计划项目（S2015YFJM1473）.

摘　　要：目的 探讨3.0T MR在兔肝脏多模态定量扫描时的技术要求。 方法 选择新西兰大白兔8只，应用3.0T MR成像系统，行肝脏T1 mapping、T2 mapping、MT序列及Gd-EOB-DTPA（0.025 mmol/kg）动态增强扫描，后者采用不同的速率（1.5 mL/s和2 mL/s）和生理盐水用量（6 mL和8 mL）进行匹配。判断各种技术的图像质量是否符合要求。 结果 全部扫描时间约为20-25 min。T1 mapping、T2 mapping、MT序列均获得满意的扫描图像。Gd-EOB-DTPA动态增强扫描时，各组间图像质量无明显差异（P〉0.05），但采用2 mL/s和8 mL的条件时，2只动物死亡。 结论 选取合适的扫描参数时，可以成功进行3.0T MR多模态兔肝脏定量成像。Objective To investigate the technical requirements for the 3.0T multi-modal quantitative MR imaging of the rabbit liver. Methods A total of 8 rabbits were scanned and T1 mapping,T2 mapping, MT and Gd-EO]-DTPA dynamic enhancement images were acquired. For the dynamic enhanced scanning, injecting contrast medium was followed by saline flush with different combinations of injection flow rate （1.5 mL/s and 2 mL/s} and injection volume（6 mL and 8 mL）. The quality of the images was assessed and analyzed statistically. Results The total scanning time was about 20-25 rain. High-quality images were acquired by T1 mapping, T2 mapping and MT sequences. There was no significant difference in image quality among different groups in Gd-EOB-DTPA dynamic enhanced scanning （P〉0.05）.Two rabbits died when the combination of injection flow rate of 2 mL/s and injection volume of 8 mL was used.Conclusion 3.0 T multi-modal quantitative MR scanning of rabbit liver can be achieved successfully if scanning parameters are properly chosen.

关 键 词：兔 肝脏 磁共振成像 

分 类 号：R332[医药卫生—人体生理学] R322.47[医药卫生—基础医学]