黄苞南星的化学成分研究  

Study on the chemical constituents of Arisaema flavum (Forsk.) Schott

作　　者：何达海[1] 梁天宇[1] 丁克毅[1] 刘军[1] 

机构地区：[1]西南民族大学药学院,四川成都610041

出　　处：《西南民族大学学报（自然科学版）》2017年第3期263-267,共5页Journal of Southwest Minzu University(Natural Science Edition)

基　　金：中央高校基本科研业务费专项基金项目(2014NZYQN16)

摘　　要：目的:旨在明确黄苞南星的化学成分,从而为研发科学合理的炮制方法以减毒增效,以及质量标准的建立提供物质基础.方法:采用硅胶正相色谱和ODS(C-18)反相色谱等方法研究黄苞南星块茎的化学成分.结果:根据理化性质和波谱数据与已知化合物对照鉴定了6个化合物.分别是脂肪酸类6,7,10-三羟基-(反)-8-十八烯酸(1),甾体化合物qingyangshengenin(2),胡萝卜苷(3),腺苷(4),豆甾醇(5)以及β-谷甾醇(6).化合物4的结构通过单晶衍射实验得到证实.结论:上述化合物为首次从该植物中所分离,进一步丰富了其二次代谢产物的种类.Objective：To clarify the chemical composition of Arisaema flavum, so as to provide data for the development of scien- tific and reasonable processing methods to reduce toxicity and improve efficiency and for the establishment quality standards. Methods：Silica gel column and reverse phase （C-18） column chromatography were used for the research of chemical constitu- ents in Arisaema flavum （ Forsk. ） Schott. The structures were elucidated by comparing physic-chemical properties and NMR spectroscopic data with those of known compounds. Results：Six compounds were identified as 6,7,10-trihydroxy-8 （E）-octade- cenoic acid （ 1 ）, steroids qingyangshengenin （ 2）, daucosterol （ 3 ）, adenosine （4） stigrnasterol （ 5 ） and β-sitosterol （6）. Compound 4 was confirmed by X-ray diffraction. Conclusion：These componds are isolated from this plant for the first time, and the metabo- lites of this plant are enriched.

关 键 词：天南星属 黄苞南星 多羟基脂肪酸 甾体 

分 类 号：R284[医药卫生—中药学]