犬钩端螺旋体病3例报告  

Three cases of canine leptospirosis

作　　者：肖园[1] 吴海燕[1] 孙艳争[1] 庞海东[1] 张海霞[1] 陈宋杰 刘洋[1] 吕艳丽[1] XIAO Yuan WU Hai-yan SUN Yan-zheng PANG Hai-dong ZHANG Hai-xia CHEN Song-jie LIU Yang LYU Yan-li(Veterinary Medicine College China Agricultural University, Beijing 100193, China)

机构地区：[1]中国农业大学动物医学院,北京100193

出　　处：《中国人兽共患病学报》2017年第5期469-471,共3页Chinese Journal of Zoonoses

基　　金：犬猫重要人兽共患病诊断及治疗技术研究(Z171100001517008)~~

摘　　要：目的探究钩端螺旋体病的发病规律和诊疗方法。方法对2015年8月至11月在中国农业大学动物医院确诊的3只钩端螺旋体病犬的发病和诊疗情况进行回顾分析。结果病犬均出现精神沉郁、黄疸、厌食和呕吐等症状,其中2例有体温升高病史,并且在发病前接触过外界水源。实验室检查3只病犬均存在肝肾损伤和贫血。依据尿液PCR检测结果为阳性确诊病犬患钩端螺旋体病。在诊疗过程中3只病犬有1只死亡,其余2只经抗菌素和对症治疗后康复。结论犬感染钩端螺旋体和接触疫水相关,尿液PCR检测可作为该病的确诊方法,治疗上推荐使用青霉素和多西环素等四环素类药物。In order to explore the pathogenic characters, diagnosis and treatment of canine leptospirosis, a retrospective analysis of the pathogenetic factor, diagnosis and treatment of three dogs were reported which diagnosed as canine leptospirosis in China Agricultural University Teaching Animal Hospital from August to November, 2015. The infected dogs showed symptoms of depressed, jaundice, anorexia and vomiting. Two of them had fever history and contacted the water resource outside before getting ill. All three dogs were confirmed anemia, liver and kidney damage by laboratory examination. They were diagnosed with canine leptospirosis according to the positive results of the Leptospira PCR examination base on urine. During the diagnosis and treatment process, one of them was dead, the rest two recovered after antibiotic and symptomatic therapy. In conclusion, dogs which infected with leptospirosis may have a contact with the infected water before. The Leptospira PCR examination base on urine can be used for the diagnosis method of the disease. As to treatment, the use of penicillin and tetracycline drugs such as doxycycline is recommended.

关 键 词：犬 钩端螺旋体 聚合酶链式反应 多西环素 

分 类 号：R514.4[医药卫生—内科学]