穴位埋线治疗糖尿病前期的疗效观察及术后反应  

Effect and postoperative reactions of acupoint catgut embedding for prediabetes

作　　者：薛宁[1] 张建斌[2] 夏兆新 笪妮丽 

机构地区：[1]句容市人民医院针灸科,江苏句容212400 [2]江苏省第二中医院针灸科,南京210013

出　　处：《中国针灸》2017年第6期586-590,共5页Chinese Acupuncture & Moxibustion

基　　金：镇江市科技支撑项目:SH 2014106

摘　　要：目的:观察评价穴位埋线治疗糖尿病前期的临床疗效和安全性。方法:将86例糖尿病前期患者随机分为观察组和对照组,每组43例。对照组进行糖尿病健康教育。观察组在对照组基础上行穴位埋线,穴取双侧脾俞、胃脘下俞、肝俞、肾俞、足三里,每15天穴位埋线1次,共完成6次穴位埋线。从第2次治疗开始,每次治疗前记录患者上次穴位埋线后的术后反应类型及次数等,于治疗结束15 d后记录最后1次穴位埋线术后情况。于治疗前后及治疗结束6个月后对两组胆固醇(total cholesterol,TC)、三酰甘油(triglyceride,TG)、空腹血糖(fasting plasma glucose,FPG)、餐后2 h血糖(2 hours postprandial blood glucose,2h PG)、糖化血红蛋白(Hb A1c)、空腹胰岛素水平(insulin,Ins)及中医证候积分情况进行记录,并评价临床疗效。结果:治疗后观察组TC、TG、FPG、2h PG、Hb A1c均低于治疗前(均P<0.05),且均低于对照组(均P<0.05),Ins较治疗前变化幅度较小,且较对照组差异无统计学意义(均P>0.05)。随访时两组各项指标较治疗前差异均无统计学意义(均P>0.05)。治疗后观察组中医证候积分低于治疗前,且低于对照组(均P<0.05)。随访时观察组中医证候积分低于治疗前,差异有统计学意义(P<0.05)。观察组总有效率为76.7%(33/43),明显优于对照组的30.2%(13/43,P<0.05);随访时观察组总有效率下降到37.2%(16/43),对照组总有效率下降到25.6%(11/43,P>0.05)。观察组患者埋线术后共记录18种术后反应,共出现168次,可分为5大类:饮食抑制现象相关的术后反应75次(44.6%),情绪异常相关的术后反应41次(24.4%),局部不适相关的术后反应23次(13.7%),全身不适相关的术后反应21次(12.5%),其他不适相关的术后反应8次(4.8%);术后反应高峰期在第2~3次穴位埋线术后。结论:3个月的穴位埋线治疗能改善糖尿病前期患者部分指标,但需长期保持健康的生活习惯,穴位埋线后可出现多种�Objective To observe the effect and safety of acupoint catgut embedding for prediabetes. Methods Eighty-six patients with prediabetes were randomly assigned into an observation group and a control group, 43 cases in each one. Diabetes health education was applied in the two groups. Catgut embedding was used at bilateral Pishu（BL 20）,Weiwanxiashu（EX-B 3）, Ganshu（BL 18）, Shenshu（BL 23）, and Zusanli（ST 36） in the observation group, once every 15 days for 6 times. The type and number of postoperative reactions of the last time had been recorded since the second embedding,and the situation of the last postoperative reactions was observed 15 days after treatment. Total cholesterol（TC）, triglyceride（TG）, fasting plasma glucose（FPG）, 2 hours postprandial blood glucose（2hP G）, glycosylated hemoglobin（Hb A1c）, empty stomach insulin（Ins） and TCM syndrome score were tested before and after treatment as well as 6 months after treatment. The clinical efficacy was evaluated. Results After treatment, the levels of TC, TG, FPG, 2hP G, Hb A1 c of the observation group were lower than those before treatment and those of the control group（all P〈0.05）. The Ins changed little after treatment and was not significantly different from that of the control group（both P〉0.05）. All the above indices had no significant difference at follow-up compared with those before treatment（all P〉0.05）. After treatment, the TCM syndrome score in the observation group was lower than that before treatment and that in the control group（both P〈0.05）. The TCM syndrome score at follow-up was better than that before treatment in the observation group（P〈0.05）. The total effective rate of the observation group was 76.7%（33/43） after treatment, which was superior to 30.2%（13/43） of the control group（P〈0.05）. The rates atfollow-up was 37.2%（16/43） in the observation group and was 25.6%（11/43） in the control group（P〉0.05）. 18 postoperative reactions occurred 168 tim

关 键 词：糖尿病前期 穴位埋线 术后反应 随机对照试验 

分 类 号：R246.1[医药卫生—针灸推拿学]