血流储备分数在冠状动脉支架植入术中的临床应用  

Application of blood flow reserve score in coronary artery stent implantation

作　　者：周利民[1] 刘玉[1] 程昭栋[1] 安成玲[1] 王自立[1] 刘亚圆[1] Zhou Limin Liu Yu Cheng Zhaodong An Chengling Wang Zili Liu Yayuan(Department of Cardiovascular Diseases, the First People＇s Hospital of Chuzhou, Chuzhou ,Anhui 239000, Chin)

机构地区：[1]滁州市第一人民医院心内科,安徽省滁州239000

出　　处：《中国基层医药》2017年第12期1859-1862,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：安徽省滁州市科技攻关项目（201405）

摘　　要：目的 探讨血流储备分数用于指导冠状动脉支架植入治疗的临床意义.方法 纳入符合标准的冠状动脉造影检查阳性的患者共46例,冠状动脉造影阳性的标准：冠状动脉血管造影证实至少有一支冠状动脉血管狭窄≥50%,结果分为对照组（24例）、观察组（22例）.结果 两组基线水平差异无统计学意义（P〉0.05）;观察组手术时间（63.20±9.92）min、置入支架数量（0.50±0.65）支及造影剂用量（182.94±39.30）mL,均明显少于对照组（手术时间：t=2.69,P=0.01;置入支架数量：t=2.56,P=0.02;造影剂用量：t=6.98,P=0.00）,对照组与观察组心绞痛及MACE发作情况差异无统计学意义.结论 血流储备分数是对冠状动脉狭窄行PCI治疗的重要指导参数.Objective To explore the clinical significance of blood flow reserve fraction in the treatment of coronary stent implantation.Methods A total of 46 patients with positive coronary angiography were included.Criteria for positive coronary angiography：coronary angiography confirmed at least a coronary artery stenosis was more than or equal to 50%.According to the results,the patients were divided into the control group（24 cases） and observation group（22 cases）.Results 1.There was no significant difference in baseline level（P〉0.05）;2.The operation time,number of stents and the contrast agent dosage of the observation group were （63.20±9.92）min,（0.50±0.65） and （182.94±39.30）mL,which were significantly less than those of the control group,the differences were statistically significant（operation time t=2.69,P=0.01;number of stents t=2.56,P=0.02;contrast agent dosage t=6.98,P=0.00）.There was no significant difference between the control group and the observation group in angina pectoris and MACE attack.Conclusion Blood flow reserve score is an important guiding parameter for PCI treatment of coronary artery stenosis.

关 键 词：冠状动脉疾病 药物洗脱支架 血流储备分数 心肌 

分 类 号：R541.4[医药卫生—心血管疾病]