天津市2004-2014年男男同性性行为感染艾滋病病例生存时间及影响因素  

Analysis of survival length and influencing factors of MSM with HIV/AIDS in Tianjin city of China from 2004 to 2014

作　　者：柳忠泉[1] 周宁[1] LIU Zhong-quan ZHOU Ning(Center for Disease Control and Prevention of Tianjin City, Tianjin 300011 , China)

机构地区：[1]天津市疾病预防控制中心,天津300011

出　　处：《中国病毒病杂志》2017年第2期149-153,共5页Chinese Journal of Viral Diseases

摘　　要：目的了解天津市男男同性性行为者(简称男同)中艾滋病病毒感染者和病人(简称HIV/AIDS)的生存时间及影响因素。方法统计2004-2014年全国艾滋病防治信息系统中天津市报告的男同HIV/AIDS,运用寿命表法和Kaplan-Meier方法计算生存时间及各年生存率,运用单因素及多因素COX回归方法对生存时间的影响因素进行相关分析。结果 1 789例男同HIV/AIDS,平均生存时间为128.74个月,1、3、5、10、11年累计生存率分别为91%、88%、86%、79%和79%;多因素COX回归分析提示抗病毒治疗、首次CD4^+T淋巴细胞计数和病例来源均是影响生存时间的因素。结论早发现、早治疗能够明显提升男同HIV/AIDS的生存时间,需进一步加强医疗机构病例的早期发现,同时应尽早地开展抗病毒治疗。Objective To study the survival length and influencing factors of men who have sex with men （MSM） with HIV/AIDS in Tianjin city of China. Methods All MSM HIV cases reported during 2004 and 2014 from the National AIDS Prevention and Control Information System were collected; life table analysis and the Kaplan-Meier method were used to calculate the survival length, survival rate. Correlation analysis was done using univariate and multivariate Cox regression method. Results A total of 1 789 cases of HIV/AIDS patients was recruited in the analysis, the average survival length was 128. 74 months; 1-, 3-, 5-, 10- and ll- year cumulative survival rates were 91%, 88%, 86%0, 79% and 79%, respectively. The multivariate Cox re- gression analysis of antiviral therapy, the first CD4 value, infection pathway and sample source were influen- cing factors of survival length. Conclusions Early detection and early treatment can significantly increase the survival length of the MSM patients with HIV/AIDS.

关 键 词：艾滋病病毒感染者和病人(HIV/AIDS) 男同性恋 生存时间 影响因素 

分 类 号：R512.91[医药卫生—内科学]