超声自动乳腺全容积成像联合彩色多普勒血流显像对乳腺癌新辅助化疗疗效评价的意义  

Significance of ABVS combined with CDFI in the evaluation of efficacy of neoadjuvant chemotherapy for breast cancer

作　　者：黄梅[1] 王树群[1] 冯娜娜[2] 许华[3] 孙建娜[4] 陈雯[5] 高峰[1] 宋红雨[1] 李静艳[1] HUANG Mei WANG Shu-qun FENG Na-na XU Hua SUN Jian-na CHEN Wen GAO Feng SONG Hong-yu LI Jing-yan(Department of Ultrasonography Department of Scientific Research Department of Pathology Department of Breast surgery Department of Radiology, Cangzhou Integrated Traditional Chinese and Western Hospital, Cangzhou 061001, China)

机构地区：[1]河北省沧州中西医结合医院超声科,沧州061001 [2]河北省沧州中西医结合医院科研科,沧州061001 [3]河北省沧州中西医结合医院病理科,沧州061001 [4]河北省沧州中西医结合医院乳腺外科,沧州061001 [5]河北省沧州中西医结合医院放射科,沧州061001

出　　处：《中国肿瘤临床与康复》2017年第5期570-574,共5页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨超声自动乳腺全容积成像(ABVS)联合彩色多普勒血流显像(CDFI)对乳腺癌新辅助化疗(NCT)疗效评价的临床意义。方法选取2013年9月至2016年3月间沧州中西医结合医院收治的行NCT治疗的64例乳腺癌患者,系统性回顾患者的临床资料,分析所有患者化疗前后原发病灶成像及血流特点。结果临床医师查体后诊断与病理学结果一致。ABVS+CDFI检查有效52例,无效12例,诊断敏感度83.3%,符合率为62.5%。患者NCT化疗前后肿瘤长度、宽度、厚度及面积和体积大小比较,差异均有统计学意义(均P<0.05)。患者化疗前后肿瘤边界清晰度、内部回声及后方回声比较,差异均有统计学意义(均P<0.05)。有效组患者中,化疗前后0~Ⅰ级和Ⅱ~Ⅲ级血流患者所占比例比较,差异均有统计学意义(均P<0.05);无效组患者中,化疗前后0~Ⅰ级和Ⅱ~Ⅲ级血流患者所占比例比较,差异均无统计学意义(均P>0.05)。患者化疗前后血流最大流速(Vmax)和阻力指数(RI)比较,差异均有统计学意义(均P<0.05)。结论 ABVS和CDFI评价乳腺癌患者行NCT后临床疗效各有优势,两者结合具有更好地准确性和科学性,可作为临床评价乳腺癌患者NCT疗效的首选方法。Objective To investigate the clinical value of automated breast volume scanner （AB- VS） combined with color Doppler flow imaging （CDFI） in the evaluation of efficacy of neoadjuvant chemo- therapy （NCT） for breast cancer. Methods Six-four patients with breast cancer receiving NCT were se- lected at Cangzhou Integrated Traditional Chinese and Western Hospitalfrom September 2013 to March 2016. Clinical data of the patients were systematicly analyzed including primary lesion imaging and charac- teristics of blood flow before and after chemotherapy. Results The evaluation result by ABVS ＋ CDFI was consistant with the pathological findings. ABVS ＋ CDFI examination showed that 52 cases were effective and 12 cases ineffective and the diagnostic sensitivity was 83.3% and the coincidence rate was 62. 5%. There was significant difference in the tumor length, width, thickness and area and volume before and after NCT chemotherapy （ all P 〈 0. 05 ）. There was significant difference in the tumor boundary definition, internal echo and posterior echo before and after the chemotherapy （ all P 〈 0. 05 ）. For the effective group, the pro- portion of patients with 0 - Ⅰ and Ⅱ-Ⅲ blood flow before and after chemotherapy （ all P 〈 0. 05 ）. For theeffective group, there was no significant difference in the proportion of patients with 0 -Ⅰ andⅡ-Ⅲ blood now before and after chemotherapy （ all P 〉 0. 05）. There was significant difference in Vmax and RI before and after chemotherapy （ all P 〈 0.05）. Conclusion The ABVS and CDFI have their own advantages in e- valuating the clinical efficacy of NCT in patients with breast cancer but the combination of the two was more accurate and scientific, which can be used as a preferred metbod in evaluating the efficacy of NCT in pa- tients with breast cancer.

关 键 词：自动乳腺全容积成像 彩色多普勒血流显像 乳腺肿瘤 新辅助化疗 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]