综合护理干预对反复种植失败冻融胚胎移植病人心理和妊娠结局的影响  

Influence of comprehensive nursing intervention on psychological and pregnancy outcome of frozen-thawed embryo transfer patients with repeated implantion failure

作　　者：吴远菲[1] 杨旭辉[1] 刘宴伟[1] 刘颖[1] 黄莉[1] 许虹[1] 

机构地区：[1]广东省妇幼保健院

出　　处：《护理研究（下旬版）》2017年第6期2210-2213,共4页Chinese Nursing Researsh

基　　金：广东省医学科学技术研究基金项目;编号:A2016562

摘　　要：[目的]探讨综合护理干预对体外受精-胚胎移植(IVF-ET)反复种植失败冻融胚胎移植(FET)病人治疗结局的影响。[方法]选择2015年1月—2015年5月在我院反复种植失败2次及以上,有冻融胚胎进行FET移植治疗周期的134例病人为研究对象,将单日入移植治疗周期的66例病人设为对照组,给予常规护理干预;双日入移植治疗周期的68例病人设为观察组,给予常规护理联合音乐疗法、耳穴按摩、药膳进行综合护理干预。在FET周期治疗启动日发放焦虑自评量表(SAS)和抑郁自评量表(SDS)评估其心理状态,并在FET移植日再次进行问卷调查。比较干预后两组病人心理状况、临床妊娠率、流产率、活产率。[结果]FET移植日对照组SAS得分为(48.62±5.04)分,SDS得分为(50.77±6.56)分,观察组SAS得分为(44.27±4.85)分,SDS得分为(46.26±7.41)分,两组比较差异有统计学意义(P<0.01);观察组临床妊娠率(60.82%)高于对照组(53.03%),流产率(5.88%)低于对照组(16.67%),两组比较差异均有统计学意义(P<0.05)。[结论]综合护理干预能有效降低反复种植失败病人的焦虑状态,缓解病人的心理压力,从而获得更好的临床治疗结局。Objective:To probe into the influence of comprehensive nursing intervention on the outcome of patients with in vitro fertilization and embryo transfer(IVF-ET)repeated implantation failure in frozen-thawed embryo transfer(FET).Methods:In January 2015-May 2015,a total of 134 patients who had failed to plant in the hospital for more than 2times and had frozen-embryo embryos were treated with FET transplantation for the study.A total of 66 patients with single-day transplant treatment were selected as control group and routine nursing intervention was given 68 cases in even-numbered day transplant treatment cycle were treated with routine nursing combined with music therapy,ear massage and medicated diet comprehensive nursing intervention.(SAS)and Depression Self Evaluated Scale(SDS)were used to assess their mental status on the starting day of FET cycle treatment and were re-questioned on the day of FET transplantation.The psychological status,implantation rate,clinical pregnancy rate abortion rate and live birth rate were compared between the two groups after intervention.Results:SAS on FET transplantation day in control group was(48.62±5.04),SDS was(50.77±6.56).SAS in observation group was(44.27±4.85),SDS was(46.26±7.41).The difference between the two groups was statistically significant(P<0.01).The clinical pregnancy rate(60.82%)in observation group was higher than that in control group(53.03%),and the abortion rate(5.88%)was lower than that in control group(16.67%).There was statisti cally significant difference between the two groups(P<0.05).Conclusion:Comprehensive nursing intervention could effectively reduce the anxiety of patients with repeated implantion failure,relieve the psychological pressure of patients,so as to obtain a better clinical outcome.

关 键 词：辅助生殖技术 体外受精-胚胎移植 种植失败 心理干预 音乐疗法 耳穴按摩 药膳 

分 类 号：R473.71[医药卫生—护理学]