2010-2014年深圳市乙型和丙型病毒性肝炎流行特征分析  

Epidemiological characteristics of viral hepatitis B and C in Shenzhen City,2010-2014

作　　者：陈国翠[1] 谢旭[2] 陈伟红[1] 吕秋莹[2] 

机构地区：[1]深圳市罗湖区疾病预防控制中心,广东深圳518000 [2]深圳市疾病预防控制中心

出　　处：《实用预防医学》2017年第7期810-813,共4页Practical Preventive Medicine

基　　金：深圳市科技研发资金知识创新计划第一批基础研究项目(JCYJ20140416104959067)

摘　　要：目的了解深圳市2010-2014年乙、丙型病毒性肝炎的流行特征,提出适宜本地病毒性肝炎的防治依据。方法收集2010-2014年中国疾病预防控制信息系统深圳市乙型和丙型病毒性肝炎网络报告病例数据并进行统计分析;随机选取本地区体检门诊2个,调查其HCV感染状况。结果深圳市2010-2014年乙型肝炎累计报告3 497例,报告发病率在6.31/10万~10.21/10万之间,平均发病率为7.58/10万;丙型肝炎累计报告613例,报告发病率在1.11/10万~1.68/10万,平均报告发病率为1.33/10万;乙肝、丙肝病例男女比例分别为11.45:1和2.70:1;丙肝慢性病例比例59.87%(367/613),乙肝慢性病例占95.08%(3 325/3 497);乙肝、丙肝本地户籍人口比例分别为81.73%(2 858/3 497)、89.07%(546/613);乙肝、丙肝报告病例中25~44岁五年累计报告数所占比例分别为58.39%(2 042/3 497)和55.63%(341/613);2014年1-12月在体检门诊共发现HCV感染者6例,感染率0.30%(6/1 983)。结论 2010-2014年深圳市乙、丙型肝炎病例报告总体感染呈下降趋势,男性多于女性,本地人口、中青年、慢性病例为主。体检门诊丙肝感染率远高于历年平均报告水平。建议规范本地传染病上报工作,加大体检覆盖人群,对体检门诊诊断发现的HCV感染者建立档案并进行转介防控,将乙、丙型肝炎防控工作纳入社区公共卫生服务体系。Objective To investigate the epidemiological features of viral hepatitis B and C in Shenzhen City from 2010 to 2014, and to put forward evidence for viral hepatitis prevention and treatment in the local areas. Methods The data regarding viral hepatitis B and C network reported cases in Shenzhen City during 2010-2014 were collected from China Disease Prevention and Control Information System and statistically analyzed. Two physical examination clinics in the local areas were randomly selected to investigate the status of hepatitis C virus infection. Results A total of 3,497 hepatitis B cases were cumulatively reported in Shenzhen City during 2010-2014, with the reported incidence rate and the average incidence rate being 6.31/100,000-10.21/ 100,000 and 7.58/100,000 respectively. A total of 613 hepatitis C cases were cumulatively reported, with the reported incidence rate and the average incidence rate being 1.11/100,000-1.68/100,000 and 1.33/100,000 respectively. The male to female ratios for hepatitis B and C cases were 11.45 ： 1 and 2.70 ： 1 respectively. The proportions of chronic hepatitis C and B cases were 59.87% （367/613） and 95.08% （3,325/3,497） respectively. The proportions of hepatitis B and C cases in the local registered population were 81.73 % （ 2,858/3,497 ） and 89.07 % （ 546/613 ） respectively. The proportions of cumulatively reported cases of hepatitis B and C in the residents aged 25-44 years during the 5-year period were 58.39% （2,042/3,497） and 55.63% （341/613） respectively. Six patients infected with HCV were detected in the physical examination clinics from January to December, 2014, with the infec- tion rate of 0.30% （6/1,983）. Conclusions The overall annual incidence rates of hepatitis B and C in Shenzhen City during 2010-2014 show a declining trend. The male cases are more than the female ones, and most of the cases are the young and middle -aged local residents with chronic hepatitis B or C. The rates of hepatitis C infection in the physical examination clin

关 键 词：丙型病毒性肝炎 乙型病毒性肝炎 流行特征 

分 类 号：R512.6[医药卫生—内科学]