芽囊原虫研究进展  

Advances in the Research of Blastocystis

作　　者：周春燕[1] 严宜明[2] 

机构地区：[1]赣南医学院,江西赣州341000 [2]赣南医学院基础医学院,江西赣州341000

出　　处：《赣南医学院学报》2017年第2期303-311,共9页JOURNAL OF GANNAN MEDICAL UNIVERSITY

基　　金：国家自然科学基金项目(No.81260255);江西省自然科学基金项目(No.20114BAB205040);江西省教育厅科技项目(No.GJJ12556)

摘　　要：芽囊原虫是一种寄生于人类及许多动物肠道中的常见单细胞厌氧真核生物。该虫不仅形态多样,而且具有高度遗传多样性。虽然芽囊原虫与胃肠道症状、肠易激综合征和荨麻疹等有关,但对其临床意义仍然存在争议。近年来,通过体外和体内研究,对芽囊原虫的病理生理学做了新的阐述,并提出了可能的致病机制。在这篇综述中,我们总结了芽囊原虫的分类学、形态学、遗传多样性、感染与疾病、致病性、诊断方法和流行病学等方面的一些研究进展。Blastocystis is a kind of common single cellular anaerobic eukaryotes that are parasites in the intestine of humans and many animals. It is not only of various forms, but also of high genetic diversity. Although Blastocystis is associated with gastrointestinal symptoms, irritable bowel syndrome （IBS） , and urticaria, its clinical significance remains controversial. In recent years, through the in vitro and in vivo studies, some new progresses have been made on the understanding of the pathophysiology of Blastocystis, and the new possible pathogenic mechanisms have been put forward. In this review, we summarized the recent research advances on the taxonomy, morphology, genetic diversity, infection and disease, pathogenicity, diagnosis, and epidemiology of Blastocystis.

关 键 词：芽囊原虫 不等鞭藻 亚型 胃肠道 

分 类 号：R382[医药卫生—医学寄生虫学]