FA值、ADC值与腰骶丛脊神经根受压程度的相关性研究  

Correlation of FA and ADC values in lumbosacral Nerve Roots Compression

作　　者：吴杏[1] 胡久益[2] 王小双[2] 刘四斌[2] 

机构地区：[1]长江大学第二临床医学院,434020 [2]荆州市中心医院放射科,434020

出　　处：《临床放射学杂志》2017年第5期710-713,共4页Journal of Clinical Radiology

摘　　要：目的探讨磁共振扩散张量成像(DTI)技术各向异性分数(FA)、表观扩散系数(ADC)与腰骶丛脊神经根受压程度的关系,评价DTI技术在腰骶丛脊神经根受压程度中的诊断价值。方法选取70例腰椎间盘突出患者行常规MRI及DTI检查,获得L_5神经根Lindblon分级(共4级)及FA值、ADC值,分析Lindblon分型与FA值、ADC值的关系,并进行双侧L_3~S_1神经根扩散张量纤维束成像(DTT)。结果患侧L_5神经根平均FA值显著低于健侧(t=-4.416,P<0.01),平均ADC值高于健侧(t=3.334,P<0.05);各级神经根平均FA值、ADC值的差异有高度统计学意义(F=50.347,P<0.01;F=53.572,P<0.01);经Spearman相关分析显示神经根受压Lindblon分级与FA值呈负相关(rs=0.970,P<0.01),与ADC值呈正相关(r_s=-0.963,P<0.01)。结论 FA值、ADC值可以反映神经根受压程度,且随着受压程度的加重,FA值降低,ADC值升高。Objective To analyze the correlation of fractional anisotropy（FA） and apparent diffusion coefficient（ADC） of diffusion tensor imaging（DTI） in lumbosacral nerve roots Compression, and assess the value of diffusion tensor imaging （DTI） in the diagnosis of lumbosacral nerve roots Compression. Methods Seventy patients with lumbar disc herniation underwent conventional MRI sequence and DTI,obtained L5 nerve root Lindblon grading（ four levels）and FA and ADC values,then analyzed the correlation of FA and ADC values in Lindblon grading and carried out diffusion tensor tractography （DTY） of bilateral L3 -S1 nerve roots. Results （1）The average FA value of L5 nerve root on the diseased side were significantly lower than that of the healthy side（t = -4. 416,P 〈0.01 ）. The average ADC values of L5 nerve root on the diseased side were higher than that of healthy side （ t = 3. 334, P 〈 0.05 ） ; （2） The difference of the average FA and ADC values in nerve roots at all levels was statistically significant （ F = 50. 347 ,P 〈 0. 01 ; F = 53. 572, P 〈 0.01 ） ; （ 3 ） There was negative correlation between FA value and Lindblon grading （ rs = 0. 970, P 〈 0.01 ）, and positive correlation between ADC value and Lindblon grading（r = - 0. 963,P 〈 0.01 ） by Spearman rank correlation test. Conclusion FA and ADC values could reflect the degree of nerve mot compression, and with the increase of the degree of compression, FA value decreased and ADC value increased.

关 键 词：腰骶丛神经根压迫症 磁共振扩散张量成像 各向异性分数 表观扩散系数 

分 类 号：R445.2[医药卫生—影像医学与核医学] R681.5[医药卫生—诊断学]