某山区B型脑钠肽在医院内肺部感染合并心力衰竭患者中的应用  

Application of B-type Brain Natriuretic Peptide in Mountain Area in Patients with Pulmonary Infection with Heart Failure

作　　者：梁林慧[1] 黄承乐[1] 农世泽[1] 余飞[1] 李春丽[1] 

机构地区：[1]百色市人民医院检验科,广西百色533000

出　　处：《中国医药指南》2017年第13期142-143,共2页Guide of China Medicine

摘　　要：目的探讨桂西山区医院感染肺部合并心力衰竭患者B-型脑尿钠肽水平变化规律,为桂西山区医院肺部感染合并心力衰竭患者的诊治提供依据。方法用化学发光法测定医院肺部感染患者合并心力衰竭患者与单纯医院肺部感染组、单纯心力衰竭组、正常对照组血浆B型脑尿钠肽水平变化以及三组患者病死率的相比较。结果医院肺部感染合并心力衰竭组的血浆B型脑尿钠肽与单纯医院肺部感染心力衰竭组、单纯心力衰竭组、对照组相比,医院肺部感染合并心力衰竭组B型脑尿钠肽水平较单纯医院肺部感染组、单纯心力衰竭组、正常对照组高(P<0.05),三者相比有统计学意义。经系统治疗后,仍无效死亡,三组的病死率比较,医院肺部感染合心力衰竭组的病死率与单纯医院肺部感染病死率、单纯心力衰竭组病死率相比,医院感染合并心力衰竭组病死率均高于其他两组(P<0.05),三者相比有统计学意义。结论桂西山区医院感染肺部患者可导致心力衰竭,血浆B型脑尿钠肽的检测,并对其诊断和预后有一定的价值。Objective To determine BNP level in Patients who had puimonary infection with heart failure in hospital of wester Guangxi, to find out diagnostic basis for pulmonary infecton with heart failure. Methods Used CLIA to measure the level of BNP in three groups. The first group is patients who had pulmonary infection with heart failure, the second group is patients who had pure hospital pulmonary infection, the third group is control. Using statistical methods to contrast the level of BNP and case fatality rate between three group. Result Compared with other group, there was a higher level of BNP in patients group which had pulmonary infection with heart failure （P〈0.05）. Compared with patients had pure pulmonary infection and pure heart failure, the patients who had pulmonary infection with heart failure had a higher mortality rates. Conclusion In patient who had pulmonary infection may cause heart failure in hospital ofwester Guangxi, and the level BNP is value for the diagnosis and prognosis.

关 键 词：B型脑钠肽 医院肺部感染 心力衰竭 

分 类 号：R541.6[医药卫生—心血管疾病]