丹栀逍遥散加减治疗肝郁气滞型黄褐斑临床观察  

Clinical Effect of Modified Danzhi Xiaoyao Powder for the Treatment of Chloasma with Stagnation of Liver-Qi Type

作　　者：廖承成[1] 赵丽娟[1] 张旭[1] 黄虹[1] 

机构地区：[1]云南中医学院第一附属医院皮肤科,云南昆明650021

出　　处：《四川中医》2017年第6期178-180,共3页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:观察丹栀逍遥散加减对肝郁气滞型黄褐斑患者的临床疗效。方法:选取我院皮肤科黄褐斑患者62例作为研究对象,随机等分为2组,对照组给予维生素C 600mg/日、维生素E 300mg/日;治疗组丹栀逍遥散加减口服,1剂/日。3疗程后,比较治疗两组患者的皮损面积、临床症状评分及临床疗效。结果:治疗前后,两组患者皮损面积及临床症状评分的组内比较,差异有统计学意义(P<0.05)。治疗后,两组患者皮损面积及临床症状评分的组间比较,差异有统计学意义(P<0.05)。治疗后,治疗组的临床有效率为96.77%,显著高于对照组的87.10%,差异有统计学意义(P<0.05)。治疗后,治疗组的SOD水平显著增加,且组间比较,差异有统计学意义(P<0.05)。结论:丹栀逍遥散加减能显著改善肝郁气滞型黄褐斑患者的临床症状,且临床有效率高,优于单纯的西药维生素C及维生素E疗法。Objective ： To analyze the clinical effect of Modified Danzhi Xiaoyao Powder on chloasma with stagnation of liver -Qi type. Methods： 62 cases of patients from dermatology department in our hospital were selected as the object, which were e- qually divided into 2 groups, randomly. Patients in the controlled group were gived Vitamin C 600 mg per day and Vitamin E 300 mg per day. Patients in the treatment group were treated with Danzhi Xiaoyao Powder, 1 dosage per day. After 3 courses of treat- ment, paoriasis area, clinical symptom score and clinical efficacy were compared between the two groups. Results： Before and after the treatment, the difference of paoriasis area, clinical symptom score within two groups was statistically significant （ P 〈 0. 05 ）. After the treatment, the difference of paoriasis area, clinical symptom score between the two groups was statistically signifi- cant （P 〈 0. 05）. After treatment, the clinical effective rate of the treatment group was 96. 77%, significantly higher than that of the controlled group 87. 10%, the difference was statistically significant （P 〈 0. 05）. After treatment, the level of SOD in the treatment group was higher than that before treatment and the controlled group after treatment, the difference was statistically significant （ P 〈 0. 05 ）. Conclusion ： Modified Danzhi Xiaoyao Powder can significantly improve the chnical symptoms of patients with stagnation of liver-Qi type, and the clinical effective rate is better than pure western medicine, vitamin C and vitamin E therapy.

关 键 词：黄褐斑 肝郁气滞型 丹栀逍遥散加减 

分 类 号：R758.42[医药卫生—皮肤病学与性病学]