绝经后骨质疏松症与踝臂脉搏波传导速度的相关性分析  

作　　者：吴文哲[1] 李跃华[2] 李小玲[1] 许亚培 朱圣文[1] 王嗣[1] 

机构地区：[1]浙江中医药大学附属第三医院,310005 [2]中国中医科学院西苑医院,100091

出　　处：《浙江临床医学》2017年第7期1251-1252,共2页Zhejiang Clinical Medical Journal

基　　金：浙江中医药大学附属第三医院院级课题（ZS15YA07）

摘　　要：目的探讨绝经后骨质疏松症（PMOP）与踝臂脉搏波传导速度的关系。方法采用双能X线骨密度仪检测243例绝经后女性腰椎、左侧髋关节骨密度，基于骨密度T值分为非骨质疏松组（116例）和骨质疏松组（127例），应用全自动动脉硬化诊断仪测定踝臂脉搏波传导速度（baPWV），比较两组踝臂脉搏波传导速度的差异及与骨密度的相关性。结果骨质疏松组踝臂脉搏波传导速度高于非骨质疏松组（t=-2．101，P=0．037）。全组踝臂脉搏波传导速度与髋部骨密度及腰椎骨密度呈负相关（P〈0．05）。骨质疏松组踝臂脉搏波传导速度与髋部骨密度及腰椎骨密度呈负相关（P〈0．05），非骨质疏松组踝臂脉搏波传导速度与腰椎骨密度无相关性（P〉0．05）。结论高水平踝臂脉搏波传导速度可能是绝经后骨质疏松症的预测因子。Objective To study the relationship between postmenopausalosteoporosis and brachial-ankle pulse wave velocity. Methods BMD of lumbar spine and left hip of 243 postmenopausal women was measured by dual-energy X-ray absorptiometry. Based on the T-scores of bone mineral density, participants were categorized into non-osteoporosis group （ 116 cases ） and osteoporosis group （ 127 cases ） , BaPWV was tested by fully automatic arteriosclerosis diagnosis instrument. Comparisons were made between the two groups for baPWV, to determine whether there were differences and their correlation with bone density. Results The difference of baPWV was statistically significant in two groups （ P〈0.05 ） , the baPWV of osteoporosis group was higher than that of non-osteoporosis group （ t=-2.104, P=0.037 ） . BaPWV was negatively correlated with BMD of left hip and lumbar spine in total group （ P〈0.05 ） . BaPWV was negatively correlated with BMD of left hip and lumbar spine in osteoporosis group （P〈0.05） , however, negative relationship didn＇t appear between baPWV and BMD of lumbar spine in non-osteoporosis group （ r=-0.145, P〉0.05 ） . Conclusions The high level ofbaPWV may be a predictive factor for postmenopausalosteoporosis.

关 键 词：绝经后骨质疏松 踝臂脉搏波传导速度 骨密度 动脉硬化 

分 类 号：R681[医药卫生—骨科学]