泮妥拉唑联合铝碳酸镁、莫沙必利治疗胆囊切除后胆汁反流性胃炎的疗效观察  

Effect Observation of Pantoprazole combined with Hydrotalcite and Mosapride in the Treatment of Patients with Bile Reflux Gastritis After-cholecystectomy

作　　者：刘晓建 

机构地区：[1]江苏省扬州市江都区丁沟镇卫生院内科,江苏扬州225235

出　　处：《中国医药指南》2017年第14期5-6,共2页Guide of China Medicine

摘　　要：目的观察泮妥拉唑联合铝碳酸镁、莫沙必利治疗胆囊切除后胆汁反流性胃炎的临床疗效。方法选取行胆囊切除术后并发胆汁反流性胃炎患者99例,随机分为A(33例)、B(33例)、C(33例),其中A组采用泮托拉唑、铝碳酸镁和莫沙必利联合治疗,B组采用铝碳酸镁和莫沙必利联合治疗,C组采用泮托拉唑和莫沙必利联合。疗程均为4周,分别观察三组的临床症状及胃镜征像的变化,确定治疗效果。结果 A、B、C三组临床总有效率分别为93.94%、75.76%、72.73%,B、C两组临床疗效均差于A组(P<0.05),但是B、C两组临床疗效比较无显著性差异(P>0.05)。结论泮妥拉唑联合铝碳酸镁、莫沙必利治疗胆囊切除后胆汁反流性胃炎效果显著,值得推广。Objective To observe the clinical curative effect of pantoprazole combined with hydrotalcite and mosapride in the treatment of patients with bile reflux gastritis after- cholecystectomy. Methods 99 patients with bile reflux gastritis after-cholecystectomy were randomly divided into A group （33 cases）, B （33 cases）, C （33 cases）.A group treated with pantoprazole plus hydrotalcite plus mosapride, group B treated with hydrotalcite plus mosapride, group C treated with pantoprazole and mosapride. The course of treatment was 4 weeks. The clinical symptoms and sign of changes gastroscopy of three groups were observed, and the therapeutic effect was determined. Results A, B, C three groups of clinical total effective rate was 93.94%, 75.76%, 72.73%, In group B and C clinical efficacy were worse than that in group A （P〈0.05） .but in group B and C, the clinical efficacy was no significant difference （P〉0.05）. Conclusion Pantoprazole combined with hydrotalcite and mosapride is effective in the treatment of patients with bile reflux gastritis after cholecystectomy. it is worth promoting.

关 键 词：泮托拉唑 铝碳酸镁 莫沙必利 胆囊切除术 胆汁反流性胃炎 

分 类 号：R563.1[医药卫生—呼吸系统]