双能CT在痛风性关节炎早期诊断的灵敏度和特异度分析  

Sensitivity and specificity of dual-energy CT in early diagnosis of gouty arthritis

作　　者：莫守崎 李依蓝[1] 蔡瑜彬[1] 许百洁[1] 薛晓倩[1] 黄伟鹏[2] 李奕琏[1] 王震汕 Mo Shouqi Li Yilan Cai Yubin Xu Baijie Xue Xiaoqian Huang Weipeng Li Yilian Wang Zhenshan(Department of Rheumatolo-gy, Jieyang Hospital Affiliated to Sun Yat-sen University （Jieyang People＇s Hospital） , Jieyang 522000, Chin)

机构地区：[1]中山大学附属揭阳医院(揭阳市人民医院)风湿肾内科,揭阳522000 [2]中山大学附属揭阳医院(揭阳市人民医院)放射科,揭阳522000

出　　处：《新医学》2017年第6期403-405,共3页Journal of New Medicine

基　　金：揭阳市科技计划项目(2015B01003)

摘　　要：目的探讨双能CT成像技术在痛风性关节炎早期诊断中的灵敏度和特异度。方法研究纳入2015年1月至2016年8月临床拟诊"痛风"病例,并对受累关节行双能CT检查,以1977年美国风湿病学会(ACR)痛风性关节炎诊断标准为"金标准",统计分析双能CT发现尿酸盐晶体在痛风性关节炎诊断中的灵敏度和特异度。结果研究共纳入44例拟诊"痛风"患者,其中37例确诊痛风性关节炎,双能CT诊断痛风性关节炎的灵敏度94.59%,特异度为100%。将痛风性关节炎患者按血尿酸是否正常分为尿酸正常组和高尿酸血症组2组,双能CT发现尿酸盐晶体的灵敏度在2组间比较差异无统计学意义。结论双能CT发现尿酸盐晶体在诊断痛风性关节炎具有重要作用,尤其在血尿酸水平正常的痛风性关节炎患者中。Objective To investigate the sensitivity and specificity of dual-energy CT in the early di-agnosis of gouty arthritis. Methods Patients suspected with gout between January 2015 and August 2016 were recruited and received dual-energy CT scan of the affected joints. The American College of Rheumatology （ACR） 1977 preliminary criteria for the classification of acute arthritis of primary gout was regarded as the gold standard. The sensitivity and specificity of dual-energy CT in diagnosing gouty arthritis were evaluated. Results A total of 44 patients suspected with gout were recruited, including 37 patients diagnosed with gouty arthritis. The sensitivity and specificity of dual-energy CT were 94. 59% and 100% , respectively. According to the uric acid level, gouty arthritis patients were divided into the normal group and high serum uric acid group. No sta-tistical significance was identified in the sensitivity of dual-energy CT in diagnosing gouty arthritis between two groups. Conclusions Dual-energy CT plays a pivotal role in the diagnosis of gouty arthritis, especially for gouty arthritis patients with normal uric acid level.

关 键 词：痛风性关节炎 双能CT 

分 类 号：R589.7[医药卫生—内分泌]