Effective preparation of 5,5'-(arylmethylene)bis(4-hydroxythiazole-2(3H)-one) in an aqueous fluoroalcohol solvent system under ultrasound irradiation at room temperature  

作　　者：Mohammad Reza Poor Heravi Mozhdeh Naghilou 

机构地区：[1]Department of Chemistry,Payame Noor University

出　　处：《Chinese Chemical Letters》2017年第5期1039-1043,共5页中国化学快报（英文版）

摘　　要：A green and convenient approach for the synthesis of a series of 5,5＇-（arylmethylene）bis（4-hydroxythiazole-2（3H）-one） by the reaction of aryl aldehydes,monochloroacetic acid and ammonium thiocyanate in water/trifluoroethanol（TFE）（1：1） under ultrasound irradiation at room temperature is described.This method provides several advantages such as environmental friendliness,shorter time,excellent yields,and simple work-up procedure.A green and convenient approach for the synthesis of a series of 5,5＇-（arylmethylene）bis（4-hydroxythiazole-2（3H）-one） by the reaction of aryl aldehydes,monochloroacetic acid and ammonium thiocyanate in water/trifluoroethanol（TFE）（1：1） under ultrasound irradiation at room temperature is described.This method provides several advantages such as environmental friendliness,shorter time,excellent yields,and simple work-up procedure.

关 键 词：Multicomponent reaction Hydrogen bonding Trifluoroethanol（TFE） Ultrasound irradiation Bis（4-hydroxythiazole-2（3H）-one） 

分 类 号：O626[理学—有机化学]