临床药师对腺垂体功能减退症患者精神异常的药学监护  

Pharmaceutical Care for One Patient with Hypopituitarism and Glucocorticoid-induced Mental Disorder Symptoms by Clinical Pharmacists

作　　者：尹寿祥[1] 姜超[1] 

机构地区：[1]马鞍山市人民医院药事科,安徽马鞍山243000

出　　处：《中国医院用药评价与分析》2017年第5期710-711,715,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:探讨临床药学参与1例腺垂体功能减退症患者精神异常的药学实践。方法:对1例老年腺垂体功能减退症药物治疗所致精神症状患者的资料进行分析。结果:患者精神症状为大剂量应用糖皮质激素所导致。临床药师积极参与患者治疗,协助临床医师调整治疗方案,将注射用氢化考的松琥珀酸钠调整为口服醋酸泼尼松片常规维持量,并给予奥氮平治疗,患者精神症状逐渐好转消失。结论:临床药师深入临床,提供合理的药物监护,有利于避免与识别药品不良反应,改善患者预后,促进临床合理用药。OBJECTIVE： To probe into the pharmaceutical care for one patient with hypopituitarism and glucocorticoid-induced mental disorder symptoms by clinical pharmacists. METHODS： Analysis was conducted on data of one patient with mental disorder induced by drug therapy for elderly adenohypophysis hypofunction. RESULTS： The mental disorder symptoms were induced by high dose of glucocorticosteroid. The clinical pharmacists actively participated into the treatment process, assisted the clinicians adjust the treatment regimen, and hydrogenation of pine sodium succinate injections were replaced by orally Prednisone acetate tablets in an conventional dose combined with olanzapine. And then patients＇ mental symptoms disappeared. CONCLUSIONS： The clinical pharmacists go into the clinic and provide rational pharmaceutical care are beneficial to avoid and recognize the adverse drug reactions, help to improve the clinical outcomes of patients and promote the rational drug use in clinic.

关 键 词：垂体功能减退 糖皮质激素 精神异常 

分 类 号：R969.3[医药卫生—药理学]