丹栀逍遥散分煎液和合煎液中芍药苷变化分析  

Analysis of Change of Paeoniflorin in Single and Mixed Decoction of Danzhi Xiaoyao Powder

作　　者：张茜[1] 李吉锋[1] 周慕荣[1] 白毕艳 韩新[1] 初日 

机构地区：[1]渭南师范学院化学与生命科学学院,药物中间体协同创新中心,陕西渭南714099

出　　处：《成都中医药大学学报》2017年第2期38-40,共3页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：国家级大学生创新创业项目(17052);渭南师范学院重点科研项目(16YKF001);渭南师范学院特色学科项目(14TSXK04)

摘　　要：目的:通过芍药苷溶出率变化研究分煎和合煎对药效的影响。方法:利用高效液相色谱法(HPLC)对于丹栀逍遥散的分煎液和合煎液中有效成分之一芍药苷的溶出量进行比对分析。结果:发现丹栀逍遥散的合煎液更有利于芍药苷的溶出。结论:建议临床采用丹栀逍遥散合煎服用汤剂的方法。The active ingredient contents peoniflorin in the Danzhi Xiaoyao Powder before and after compound were detected by HPLC to confirmation if this reclpel is suit for clinical use. The results show that there are more peoniflorin in the mixed decotion. The drug effect will more clear. This experiment shows that single decoction of Danzhi Xiaoyao Powder do not suit for clinical application.

关 键 词：丹栀逍遥散 芍药苷 分煎 合煎 溶出量 

分 类 号：R289.5[医药卫生—方剂学] R284[医药卫生—中药学]