经皮穴位电刺激治疗儿童孤独症的初步研究  

A Preliminary Study on Effect of Transcutaneous Electrical Acupoint Stimulation for Children with Autism

作　　者：张纪水[1] 张秀婷 邹丽萍[3] 张嵘[4] 韩松平[4] 韩济生[4] 

机构地区：[1]首都医科大学附属北京儿童医院神经内科,北京100045 [2]北京童康疗育中心,河北涿州072750 [3]中国人民解放军总医院儿科,北京100853 [4]北京大学神经科学研究所,北京大学基础医学院神经生物学系,神经科学教育部重点实验室,卫生部神经科学重点实验室,北京100191

出　　处：《针刺研究》2017年第3期249-253,共5页Acupuncture Research

基　　金：卫生部行业专项基金(No.201302002)

摘　　要：目的:观察经皮穴位电刺激(TEAS)对孤独症儿童行为矫正训练的增强作用。方法:41名参加行为矫正的孤独症儿童随机分为训练组(n=20)与训练+TEAS组(n=21)。训练组仅接受行为矫正训练,训练+TEAS组在矫正训练基础上加TEAS合谷、内关、足三里、三阴交,30min/次,1次/d,连续治疗3个月。采用孤独症行为量表(ABC)、儿童孤独症相关量表(CARS)、Conner’s父母行为问卷(PSQ)来评估治疗效果。结果:治疗后,两组ABC量表分值均明显降低(P<0.001),训练+TEAS组较训练组降低更显著、前后变化值更大(P<0.01)。训练组显效率为5.0%(1/20),训练+TEAS组显效率为38.1%(8/21),差异具有统计学意义(P<0.05)。两组CARS分值均较治疗前明显降低(P<0.0001),训练+TEAS组较训练组降低更显著、前后变化值更大(P<0.0001)。两组PSQ评分均较治疗前显著降低(P<0.001)。TEAS干预对6岁以下的中重度患者疗效更好。结论:加用TEAS可以显著改善孤独症儿童行为矫正后的核心症状。Objective To investigate the clinical efficacy of transcutaneous electrical acupoint stimulation （TEAS） in treating children with autism spectrum disorders. Methods Forty-one autistic children receiving rehabilitation training were randomized into TEAS （n = 21） and control （n = 20） groups. The control group only received rehabilitation training. The TEAS group received both rehabilitation training and TEAS treatment [2 Hz/15 Hz alternating frequencies through two pairs of skin electrodes placed at Hegu （LI 4）-Neiguan （PC 6） on unilateral side, and Zusanli （ST 36）-Sanyinjiao （SP 6） on the contralateral side]. The treatment was given 30 min per day for 12 weeks. The outcome assessment was quantified with a series of rating scales including Autism Behavior Checklist （ABC）, Childhood Autism Rating Scale （CARS） and Parent Symptom Questionnaire （PSQ）. Results （1） The TEAS group showed more significant improvement than the control group in ABC （P〈0.01）. 38.1% effective rate （8/21） was observed in the TEAS group compared to 5.0 % （1/20） in the control group （P〈0.05）. The CARS scores of both groups were reduced （P〈0. 0001） after treatment. The TEAS group showed significantly lower score compared to the control group （ P〈0. 0001 ）. （2）There was a distinctly reduced PSQ score in both TEAS and control groups （P〈0.001 ） after treatment. （3）TEAS intervention showed better effect in children under 6 years old with moderate or severe autistic symptoms. Conclusion TEAS intervention can significantly improve the autistic symptoms.

关 键 词：孤独症 经皮穴位电刺激 孤独症行为量表 儿童孤独症相关量表 

分 类 号：R245.97[医药卫生—针灸推拿学]