郑州市二七区2016年医院就诊人群HCV感染状况调查  

Investigation on HCV Infection Status Among the Hospital in Erqi District of Zhengzhou City in 2016

作　　者：尚学兰[1] 陈妍[2] 曹杰斌[1] 王肃[1] 秦利娟[1] 李洁[3] 

机构地区：[1]郑州市二七区疾病预防控制中心,河南郑州450052 [2]郑州市第二人民医院,河南郑州450052 [3]河南省疾病预防控制中心,河南郑州450016

出　　处：《河南科技大学学报（医学版）》2017年第2期140-143,共4页Journal of Henan University of Science & Technology:Medical Science

摘　　要：目的了解郑州市二七区综合医院和传染病医院就诊人群HCV感染状况,为其他地区开展HCV感染状况调查提供参考。方法采用随机抽样,抽取辖区2级及以上综合医院和传染病医院各一家,比较2016年全年就诊者丙肝阳性率。2016年1月在综合医院按照年龄和性别分层抽样收集1 000例就诊者(肝病科、消化科、感染科等与肝炎有密切关系的科室就诊者除外)进行丙型肝炎抗体和核酸的检测,传染病医院2016年全年就诊者丙型肝炎抗体和核酸的检测。结果 2016年二七区综合医院和传染病医院就诊人群的丙肝检测阳性率分别是0.71%(304/42970)和11.25%(1 932/17 166),差异具有统计学意义(χ~2=3811.572,P=0.000)。1 000例综合医院普通就诊人群的抗-HCV阳性率0.80%(8/1000),HCV RNA阳性率0.70%(7/1000),与2012年河南省开展丙肝人群调查数据相比,差异无统计学意义。结论郑州市二七区综合医院普通就诊人群丙型肝炎呈低流行状态,综合医院普通就诊人群HCV阳性率可以在一定程度上反映普通人群阳性率。Objective To understand the epidemiologieal characteristics of hepatitis C among the crowd seeking medical in general hospital and the infectious disease hospital in Erqi District of Zhengzhou and provide the reference of investigating hepatitis C for the other areas. Methods Random sampling was used to select one general hospital and one infectious disease hospital in Erqi District of Zhengzhou. The positive rates of HCV in 2016 were compared in two hospitals. Investagation was done in the crowd seeking medical in the general hospital by age and sex stratified sampling which sample size was 1 000 cases. Blood samples were collected and detected for anti-HCV and hepatitis C virus. All patients in infectious disease hospital were detected all the year. Results The positive rates of HCV in the crowd seeking medical were respectively 0.71% （304/42 970） and 11.25% （1 932/17 166）in 2016 in general hospital and the infectious disease hospital, which was significant difference in statistics （χ^2=3811. 572,P = 0. 000）. In 1 000 cases from general crowd seeking medical, the positive rates of anti-HCV and HCV RNA were 0.80% （8/1 000） and 0.70% （7/1 000） ,respectively. Compared with the data of HCV in Hennan province in 2012, there were no significant difference in statistics. Conclusion It was low prevalent for HCV infection among the general crowd seeking medical in Erqi District of Zhengzhou. The HCV positive rate among general population could be reflected in some extent by that among the general crowd seeking medical of general hospital.

关 键 词：丙型肝炎 综合医院 流行病学 

分 类 号：R181.81[医药卫生—流行病学] R183.4[医药卫生—公共卫生与预防医学]